Graft Tolerance with Donor Alloantigen Administration

Flye, M Wayne

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI042967-02
• Application #: 6349859
• Study Section: Surgery, Anesthesiology and Trauma Study Section (SAT)
• Program Officer: Prasad, Shiv A
• Project Start: 2000-02-15
• Project End: 2005-01-31
• Budget Start: 2001-02-01
• Budget End: 2002-01-31
• Support Year: 2
• Fiscal Year: 2001
• Total Cost: $324,714

Institution

• Name: Washington University
• Department: Surgery
• Type: Schools of Medicine
• DUNS #: 062761671
• City: Saint Louis
• State: MO
• Country: United States
• Zip Code: 63130

Publications

Margenthaler, Julie A; Flye, M Wayne (2005) The immunologic function of 1B2+ double negative (CD4-CD8-) T cells in the 2C transgenic mouse. J Surg Res 126:160-6

Asakura, Hiroyuki; Takayashiki, Tsukasa; Ku, Grace et al. (2005) The persistence of regulatory cells developing after rat spontaneous liver acceptance. Surgery 138:329-34

Asakura, Hiroyuki; Ku, Grace; Kataoka, Masaaki et al. (2004) Regulatory cells develop after the spontaneous acceptance of rat liver allografts. Surgery 136:532-6

Margenthaler, Julie A; Kataoka, Masaaki; Flye, M Wayne (2004) Peripheral tolerance in transgenic mice expressing class I MHC L(d) only on cardiac cells. Transpl Immunol 12:133-41

Margenthaler, Julie A; Kataoka, Masaaki; Flye, Wayne M (2004) Oral and portal venous tolerance in the interferon-gamma knockout (GKO) mouse. J Surg Res 119:107-12

Margenthaler, Julie A; Kataoka, Masaaki; Flye, M Wayne (2003) Donor-specific antigen transfusion-mediated skin-graft tolerance results from the peripheral deletion of donor-reactive CD8+ T cells. Transplantation 75:2119-27

Kataoka, Masaaki; Margenthaler, Julie A; Ku, Grace et al. (2003) Development of infectious tolerance after donor-specific transfusion and rat heart transplantation. J Immunol 171:204-11

Margenthaler, Julie A; Landeros, Keith; Kataoka, Masaaki et al. (2003) Effects of endotoxin tolerance on Propionibacterium acnes-primed lipopolysaccharide hepatic injury. J Surg Res 112:102-10

Kataoka, Masaaki; Margenthaler, Julie A; Ku, Grace et al. (2003) ""Infectious tolerance"" develops after the spontaneous acceptance of Lewis-to-Dark Agouti rat liver transplants. Surgery 134:227-34

Kataoka, Masaaki; Shimizu, Yoshiaki; Margenthaler, Julie A et al. (2002) Transfer of ""infectious"" cardiac allograft tolerance induced by donor-specific transfusion. Surgery 132:167-72