Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI043228-02
Application #
2673220
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1997-09-30
Project End
2000-08-31
Budget Start
1998-09-01
Budget End
1999-08-31
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Chicago
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Jamieson, S E; Peixoto-Rangel, A L; Hargrave, A C et al. (2010) Evidence for associations between the purinergic receptor P2X(7) (P2RX7) and toxoplasmosis. Genes Immun 11:374-83
Hutson, Samuel L; Mui, Ernest; Kinsley, Karen et al. (2010) T. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrest. PLoS One 5:e14057
Mui, Ernest J; Schiehser, Guy A; Milhous, Wilbur K et al. (2008) Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo. PLoS Negl Trop Dis 2:e190
Welti, Ruth; Mui, Ernie; Sparks, Alexis et al. (2007) Lipidomic analysis of Toxoplasma gondii reveals unusual polar lipids. Biochemistry 46:13882-90
Lu, J Z; Muench, S P; Allary, M et al. (2007) Type I and type II fatty acid biosynthesis in Eimeria tenella: enoyl reductase activity and structure. Parasitology 134:1949-62
Ferguson, D J P; Campbell, S A; Henriquez, F L et al. (2007) Enzymes of type II fatty acid synthesis and apicoplast differentiation and division in Eimeria tenella. Int J Parasitol 37:33-51
Muench, Stephen P; Prigge, Sean T; Zhu, Liqun et al. (2006) Expression, purification and preliminary crystallographic analysis of the Toxoplasma gondii enoyl reductase. Acta Crystallogr Sect F Struct Biol Cryst Commun 62:604-6
Richards, Thomas A; Dacks, Joel B; Campbell, Samantha A et al. (2006) Evolutionary origins of the eukaryotic shikimate pathway: gene fusions, horizontal gene transfer, and endosymbiotic replacements. Eukaryot Cell 5:1517-31
Henriquez, Fiona L; Richards, Thomas A; Roberts, Fiona et al. (2005) The unusual mitochondrial compartment of Cryptosporidium parvum. Trends Parasitol 21:68-74
Mui, Ernest J; Jacobus, David; Milhous, Wilbur K et al. (2005) Triazine Inhibits Toxoplasma gondii tachyzoites in vitro and in vivo. Antimicrob Agents Chemother 49:3463-7

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