Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI043534-04
Application #
6632017
Study Section
Immunobiology Study Section (IMB)
Program Officer
Kirkham, Perry M
Project Start
2000-06-01
Project End
2005-05-31
Budget Start
2003-06-01
Budget End
2004-05-31
Support Year
4
Fiscal Year
2003
Total Cost
$273,000
Indirect Cost

  Institution

Name
University of Massachusetts Medical School Worcester
Department
Genetics
Type
Schools of Medicine
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655

  Publications

Selimyan, Roza; Gerstein, Rachel M; Ivanova, Irina et al. (2013) Localized DNA demethylation at recombination intermediates during immunoglobulin heavy chain gene assembly. PLoS Biol 11:e1001475
Guikema, Jeroen E J; Gerstein, Rachel M; Linehan, Erin K et al. (2011) Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge. J Immunol 186:1943-50
Priyadharshini, Bhavana; Welsh, Raymond M; Greiner, Dale L et al. (2010) Maturation-dependent licensing of naive T cells for rapid TNF production. PLoS One 5:e15038
Castro, Iris; Wright, Jacqueline A; Damdinsuren, Bazarragchaa et al. (2009) B cell receptor-mediated sustained c-Rel activation facilitates late transitional B cell survival through control of B cell activating factor receptor and NF-kappaB2. J Immunol 182:7729-37
Gerstein, Rachel M (2009) Deciding the decider: Mef2c in hematopoiesis. Nat Immunol 10:235-6
Coles, Andrew H; Marfella, Concetta G A; Imbalzano, Anthony N et al. (2008) p37Ing1b regulates B-cell proliferation and cooperates with p53 to suppress diffuse large B-cell lymphomagenesis. Cancer Res 68:8705-14
Pilbeam, Kristy; Basse, Per; Brossay, Laurent et al. (2008) The ontogeny and fate of NK cells marked by permanent DNA rearrangements. J Immunol 180:1432-41
Kuo, Ya-Huei; Gerstein, Rachel M; Castilla, Lucio H (2008) Cbfbeta-SMMHC impairs differentiation of common lymphoid progenitors and reveals an essential role for RUNX in early B-cell development. Blood 111:1543-51
Hoek, Kristen L; Antony, Pierre; Lowe, John et al. (2006) Transitional B cell fate is associated with developmental stage-specific regulation of diacylglycerol and calcium signaling upon B cell receptor engagement. J Immunol 177:5405-13
Borghesi, Lisa; Hsu, Lih-Yun; Miller, Juli P et al. (2004) B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors. J Exp Med 199:491-502

Showing the most recent 10 out of 14 publications