Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI043615-04
Application #
6511052
Study Section
Special Emphasis Panel (ZRG1-MBC-1 (01))
Program Officer
Schmitt, Clare K
Project Start
1999-05-01
Project End
2004-04-30
Budget Start
2002-05-01
Budget End
2003-04-30
Support Year
4
Fiscal Year
2002
Total Cost
$348,328
Indirect Cost
Name
University of Maryland Baltimore
Department
Pediatrics
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Cappello, Renato E; Estrada-Gutierrez, Guadalupe; Irles, Claudine et al. (2011) Effects of the plasmid-encoded toxin of enteroaggregative Escherichia coli on focal adhesion complexes. FEMS Immunol Med Microbiol 61:301-14
Ruiz-Perez, Fernando; Wahid, Rezwanul; Faherty, Christina S et al. (2011) Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteins. Proc Natl Acad Sci U S A 108:12881-6
Harrington, Susan M; Sheikh, Jalaluddin; Henderson, Ian R et al. (2009) The Pic protease of enteroaggregative Escherichia coli promotes intestinal colonization and growth in the presence of mucin. Infect Immun 77:2465-73
Velarde, Jorge J; Nataro, James P (2004) Hydrophobic residues of the autotransporter EspP linker domain are important for outer membrane translocation of its passenger. J Biol Chem 279:31495-504
Dutta, Pinaki R; Sui, Bao Quan; Nataro, James P (2003) Structure-function analysis of the enteroaggregative Escherichia coli plasmid-encoded toxin autotransporter using scanning linker mutagenesis. J Biol Chem 278:39912-20
Sui, Bao Quan; Dutta, Pinaki R; Nataro, James P (2003) Intracellular expression of the plasmid-encoded toxin from enteroaggregative Escherichia coli. Infect Immun 71:5364-70
Dutta, Pinaki R; Cappello, Renato; Navarro-Garcia, Fernando et al. (2002) Functional comparison of serine protease autotransporters of enterobacteriaceae. Infect Immun 70:7105-13
Behrens, Martin; Sheikh, Jalaluddin; Nataro, James P (2002) Regulation of the overlapping pic/set locus in Shigella flexneri and enteroaggregative Escherichia coli. Infect Immun 70:2915-25
Navarro-Garcia, F; Canizalez-Roman, A; Luna, J et al. (2001) Plasmid-encoded toxin of enteroaggregative Escherichia coli is internalized by epithelial cells. Infect Immun 69:1053-60
Henderson, I R; Nataro, J P (2001) Virulence functions of autotransporter proteins. Infect Immun 69:1231-43

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