Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI043876-03
Application #
6373967
Study Section
Special Emphasis Panel (ZRG1-AARR-2 (03))
Program Officer
Sharma, Opendra K
Project Start
1999-05-01
Project End
2003-04-30
Budget Start
2001-05-01
Budget End
2003-04-30
Support Year
3
Fiscal Year
2001
Total Cost
$170,783
Indirect Cost
Name
Thomas Jefferson University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Julio, Steven M; Inatsuka, Carol S; Mazar, Joseph et al. (2009) Natural-host animal models indicate functional interchangeability between the filamentous haemagglutinins of Bordetella pertussis and Bordetella bronchiseptica and reveal a role for the mature C-terminal domain, but not the RGD motif, during infection. Mol Microbiol 71:1574-90
Williams, Corinne L; Haines, Robert; Cotter, Peggy A (2008) Serendipitous discovery of an immunoglobulin-binding autotransporter in Bordetella species. Infect Immun 76:2966-77
Mazar, Joseph; Cotter, Peggy A (2007) New insight into the molecular mechanisms of two-partner secretion. Trends Microbiol 15:508-15
Cotter, Peggy A; Stibitz, Scott (2007) c-di-GMP-mediated regulation of virulence and biofilm formation. Curr Opin Microbiol 10:17-23
Williams, Corinne L; Cotter, Peggy A (2007) Autoregulation is essential for precise temporal and steady-state regulation by the Bordetella BvgAS phosphorelay. J Bacteriol 189:1974-82
Mazar, Joseph; Cotter, Peggy A (2006) Topology and maturation of filamentous haemagglutinin suggest a new model for two-partner secretion. Mol Microbiol 62:641-54
Fang, Jianhua; Acheampong, Edward; Dave, Rajnish et al. (2005) The RNA helicase DDX1 is involved in restricted HIV-1 Rev function in human astrocytes. Virology 336:299-307
Fang, Jianhua; Kubota, Satoshi; Yang, Bin et al. (2004) A DEAD box protein facilitates HIV-1 replication as a cellular co-factor of Rev. Virology 330:471-80
Gallego, Jose; Greatorex, Jane; Zhang, Hui et al. (2003) Rev binds specifically to a purine loop in the SL1 region of the HIV-1 leader RNA. J Biol Chem 278:40385-91
Dave, Rajnish S; Pomerantz, Roger J (2003) RNA interference: on the road to an alternate therapeutic strategy! Rev Med Virol 13:373-85

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