Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI045153-10
Application #
6475536
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Hall, Robert H
Project Start
2000-01-01
Project End
2004-11-30
Budget Start
2001-12-01
Budget End
2002-11-30
Support Year
10
Fiscal Year
2002
Total Cost
$280,017
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Thakur, Meena S; Khurana, Archana; Kronenberg, Mitchell et al. (2014) Synthesis of a 2""-deoxy-?-GalCer. Molecules 19:10090-102
Poussin, Mathilde A; Goldfine, Howard (2010) Evidence for the involvement of ActA in maturation of the Listeria monocytogenes phagosome. Cell Res 20:109-12
Poussin, Mathilde A; Leitges, Michael; Goldfine, Howard (2009) The ability of Listeria monocytogenes PI-PLC to facilitate escape from the macrophage phagosome is dependent on host PKCbeta. Microb Pathog 46:1-5
Chen, Wei; Goldfine, Howard; Ananthanarayanan, Bharath et al. (2009) Listeria monocytogenes phosphatidylinositol-specific phospholipase C: Kinetic activation and homing in on different interfaces. Biochemistry 48:3578-92
Aygun-Sunar, Semra; Bilaloglu, Rahmi; Goldfine, Howard et al. (2007) Rhodobacter capsulatus OlsA is a bifunctional enzyme active in both ornithine lipid and phosphatidic acid biosynthesis. J Bacteriol 189:8564-74
Aygun-Sunar, Semra; Mandaci, Sevnur; Koch, Hans-George et al. (2006) Ornithine lipid is required for optimal steady-state amounts of c-type cytochromes in Rhodobacter capsulatus. Mol Microbiol 61:418-35
Wei, Zhengyu; Zenewicz, Lauren A; Goldfine, Howard (2005) Listeria monocytogenes phosphatidylinositol-specific phospholipase C has evolved for virulence by greatly reduced activity on GPI anchors. Proc Natl Acad Sci U S A 102:12927-31
Poussin, Mathilde A; Goldfine, Howard (2005) Involvement of Listeria monocytogenes phosphatidylinositol-specific phospholipase C and host protein kinase C in permeabilization of the macrophage phagosome. Infect Immun 73:4410-3
Montes, L-Ruth; Goni, Felix M; Johnston, Norah C et al. (2004) Membrane fusion induced by the catalytic activity of a phospholipase C/sphingomyelinase from Listeria monocytogenes. Biochemistry 43:3688-95
Zenewicz, Lauren A; Skinner, Jason A; Goldfine, Howard et al. (2004) Listeria monocytogenes virulence proteins induce surface expression of Fas ligand on T lymphocytes. Mol Microbiol 51:1483-92

Showing the most recent 10 out of 12 publications