Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI045297-03
Application #
6170679
Study Section
Special Emphasis Panel (ZRG1-AARR-1 (01))
Program Officer
Plaeger, Susan F
Project Start
1999-07-01
Project End
2002-06-30
Budget Start
2000-07-01
Budget End
2001-06-30
Support Year
3
Fiscal Year
2000
Total Cost
$247,366
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Anderson, Jeffrey A; Archin, Nancie M; Ince, William et al. (2011) Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells. J Virol 85:5220-3
Archin, Nancie M; Cheema, Manzoor; Parker, Daniel et al. (2010) Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection. PLoS One 5:e9390
Keedy, Kara S; Margolis, David M (2010) Therapy for persistent HIV. Trends Pharmacol Sci 31:206-11
Bowman, Mary-Catherine; Archin, Nancie M; Margolis, David M (2009) Pharmaceutical approaches to eradication of persistent HIV infection. Expert Rev Mol Med 11:e6
Keedy, Kara S; Archin, Nancie M; Gates, Adam T et al. (2009) A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. J Virol 83:4749-56
Bowman, Mary-Catherine; Ballard, T Eric; Ackerson, Christopher J et al. (2008) Inhibition of HIV fusion with multivalent gold nanoparticles. J Am Chem Soc 130:6896-7
Klichko, Vladimir; Archin, Nancy; Kaur, Rupinderjeet et al. (2006) Hexamethylbisacetamide remodels the human immunodeficiency virus type 1 (HIV-1) promoter and induces Tat-independent HIV-1 expression but blunts cell activation. J Virol 80:4570-9
Lehrman, Ginger; Hogue, Ian B; Palmer, Sarah et al. (2005) Depletion of latent HIV-1 infection in vivo: a proof-of-concept study. Lancet 366:549-55
Ylisastigui, Loyda; Kaur, Rupinderjeet; Johnson, Holly et al. (2005) Mitogen-activated protein kinases regulate LSF occupancy at the human immunodeficiency virus type 1 promoter. J Virol 79:5952-62
Ylisastigui, Loyda; Archin, Nancie M; Lehrman, Ginger et al. (2004) Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression. AIDS 18:1101-8

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