Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI045356-04
Application #
6510991
Study Section
Special Emphasis Panel (ZRG1-AARR-6 (01))
Program Officer
Gezmu, Misrak
Project Start
1999-04-01
Project End
2003-09-30
Budget Start
2002-04-01
Budget End
2003-09-30
Support Year
4
Fiscal Year
2002
Total Cost
$231,996
Indirect Cost
Name
Frontier Sci & Technology Rsch Fdn, Inc
Department
Type
DUNS #
080330186
City
Boston
State
MA
Country
United States
Zip Code
02215
Wu, Hulin (2005) Statistical methods for HIV dynamic studies in AIDS clinical trials. Stat Methods Med Res 14:171-92
Wu, Hulin; Lathey, Janet; Ruan, Ping et al. (2004) Relationship of plasma HIV-1 RNA dynamics to baseline factors and virological responses to highly active antiretroviral therapy in adolescents (aged 12-22 years) infected through high-risk behavior. J Infect Dis 189:593-601
Liang, Hua; Wu, Hulin; Carroll, Raymond J (2003) The relationship between virologic and immunologic responses in AIDS clinical research using mixed-effects varying-coefficient models with measurement error. Biostatistics 4:297-312
Wu, Hulin; Mellors, John; Ruan, Ping et al. (2003) Viral dynamics and their relations to baseline factors and longer term virologic responses in treatment-naive HIV-1-infected patients receiving abacavir in combination with HIV-1 protease inhibitors. J Acquir Immune Defic Syndr 33:557-63
Haas, David W; Wu, Hulin; Li, Haihong et al. (2003) MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study. J Acquir Immune Defic Syndr 34:295-8
Huang, Yangxin; Rosenkranz, Susan L; Wu, Hulin (2003) Modeling HIV dynamics and antiviral response with consideration of time-varying drug exposures, adherence and phenotypic sensitivity. Math Biosci 184:165-86
Wu, Hulin; Wu, Lang (2002) Identification of significant host factors for HIV dynamics modelled by non-linear mixed-effects models. Stat Med 21:753-71
Wu, Hulin; Zhang, Jin-Ting (2002) The study of long-term HIV dynamics using semi-parametric non-linear mixed-effects models. Stat Med 21:3655-75
Wu, H; Wu, L (2001) A multiple imputation method for missing covariates in non-linear mixed-effects models with application to HIV dynamics. Stat Med 20:1755-69
Wu, H; Connick, E; Kuritzkes, D R et al. (2001) Multiple CD4+ cell kinetic patterns and their relationships with baseline factors and virological responses in HIV type 1 patients receiving highly active antiretroviral therapy. AIDS Res Hum Retroviruses 17:1231-40

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