Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI045406-04
Application #
6497283
Study Section
Special Emphasis Panel (ZRG1-AARR-2 (01))
Program Officer
Plaeger, Susan F
Project Start
1999-02-15
Project End
2004-01-31
Budget Start
2002-02-01
Budget End
2003-01-31
Support Year
4
Fiscal Year
2002
Total Cost
$423,235
Indirect Cost
Name
Immune Disease Institute, Inc.
Department
Type
DUNS #
115524410
City
Boston
State
MA
Country
United States
Zip Code
02115
Lieberman, Judy (2004) Tracking the killers: how should we measure CD8 T cells in HIV infection? AIDS 18:1489-93
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Song, Erwei; Lee, Sang-Kyung; Wang, Jie et al. (2003) RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 9:347-51
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Lieberman, J; Shankar, P; Manjunath, N et al. (2001) Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection. Blood 98:1667-77
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Chen, G; Shankar, P; Lange, C et al. (2001) CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection. Blood 98:156-64
Trimble, L A; Kam, L W; Friedman, R S et al. (2000) CD3zeta and CD28 down-modulation on CD8 T cells during viral infection. Blood 96:1021-9
Trimble, L A; Shankar, P; Patterson, M et al. (2000) Human immunodeficiency virus-specific circulating CD8 T lymphocytes have down-modulated CD3zeta and CD28, key signaling molecules for T-cell activation. J Virol 74:7320-30

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