Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI045450-04
Application #
6510995
Study Section
Special Emphasis Panel (ZRG1-AARR-2 (01))
Program Officer
Wassef, Nabila M
Project Start
1999-03-01
Project End
2005-02-28
Budget Start
2002-03-01
Budget End
2005-02-28
Support Year
4
Fiscal Year
2002
Total Cost
$257,277
Indirect Cost
Name
Temple University
Department
Miscellaneous
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Garriga, Judit; Xie, Hongbo; Obradovic, Zoran et al. (2010) Selective control of gene expression by CDK9 in human cells. J Cell Physiol 222:200-8
Salerno, Dominic; Hasham, Muneer G; Marshall, Renee et al. (2007) Direct inhibition of CDK9 blocks HIV-1 replication without preventing T-cell activation in primary human peripheral blood lymphocytes. Gene 405:65-78
Marshall, Renee M; Grana, Xavier (2006) Mechanisms controlling CDK9 activity. Front Biosci 11:2598-613
Marshall, Renee M; Salerno, Dominic; Garriga, Judit et al. (2005) Cyclin T1 expression is regulated by multiple signaling pathways and mechanisms during activation of human peripheral blood lymphocytes. J Immunol 175:6402-11
Calbo, J; Serna, C; Garriga, J et al. (2004) The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity. Cell Death Differ 11:1055-65
Garriga, Judit; Grana, Xavier (2004) Cellular control of gene expression by T-type cyclin/CDK9 complexes. Gene 337:15-23
Garriga, Judit; Jayaraman, Arun L; Limon, Ana et al. (2004) A dynamic equilibrium between CDKs and PP2A modulates phosphorylation of pRB, p107 and p130. Cell Cycle 3:1320-30
Garriga, Judit; Bhattacharya, Sabyasachi; Calbo, Joaquim et al. (2003) CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2. Mol Cell Biol 23:5165-73
Bhattacharya, Sabyasachi; Garriga, Judit; Calbo, Joaquim et al. (2003) SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells. Oncogene 22:2443-51
Calbo, Joaquim; Parreno, Matilde; Sotillo, Elena et al. (2002) G1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression. J Biol Chem 277:50263-74

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