Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI047056-05
Application #
6759259
Study Section
Special Emphasis Panel (ZRG1-AARR-1 (02))
Program Officer
Gupta, Kailash C
Project Start
1999-12-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
5
Fiscal Year
2004
Total Cost
$339,750
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

Joyner, Amanda S; Willis, Jordan R; Crowe Jr, James E et al. (2011) Maturation-induced cloaking of neutralization epitopes on HIV-1 particles. PLoS Pathog 7:e1002234
Pion, Marjorie; Arrighi, Jean-Francois; Jiang, Jiyang et al. (2007) Analysis of HIV-1-X4 fusion with immature dendritic cells identifies a specific restriction that is independent of CXCR4 levels. J Invest Dermatol 127:319-23
Jiang, Jiyang; Aiken, Christopher (2007) Maturation-dependent human immunodeficiency virus type 1 particle fusion requires a carboxyl-terminal region of the gp41 cytoplasmic tail. J Virol 81:9999-10008
Davis, Melody R; Jiang, Jiyang; Zhou, Jing et al. (2006) A mutation in the human immunodeficiency virus type 1 Gag protein destabilizes the interaction of the envelope protein subunits gp120 and gp41. J Virol 80:2405-17
Jiang, Jiyang; Aiken, Christopher (2006) Maturation of the viral core enhances the fusion of HIV-1 particles with primary human T cells and monocyte-derived macrophages. Virology 346:460-8
Wyma, Donald J; Jiang, Jiyang; Shi, Jiong et al. (2004) Coupling of human immunodeficiency virus type 1 fusion to virion maturation: a novel role of the gp41 cytoplasmic tail. J Virol 78:3429-35
Zhou, J; Aiken, C (2001) Nef enhances human immunodeficiency virus type 1 infectivity resulting from intervirion fusion: evidence supporting a role for Nef at the virion envelope. J Virol 75:5851-9
Wyma, D J; Kotov, A; Aiken, C (2000) Evidence for a stable interaction of gp41 with Pr55(Gag) in immature human immunodeficiency virus type 1 particles. J Virol 74:9381-7