Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI050083-02
Application #
6688313
Study Section
Experimental Virology Study Section (EVR)
Program Officer
Park, Eun-Chung
Project Start
2002-12-15
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$541,818
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Pediatrics
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

Beachboard, Dia C; Anderson-Daniels, Jordan M; Denison, Mark R (2015) Mutations across murine hepatitis virus nsp4 alter virus fitness and membrane modifications. J Virol 89:2080-9
Freeman, Megan Culler; Peek, Christopher T; Becker, Michelle M et al. (2014) Coronaviruses induce entry-independent, continuous macropinocytosis. MBio 5:e01340-14
Freeman, Megan Culler; Graham, Rachel L; Lu, Xiaotao et al. (2014) Coronavirus replicase-reporter fusions provide quantitative analysis of replication and replication complex formation. J Virol 88:5319-27
Beachboard, Dia C; Lu, Xiaotao; Baker, Susan C et al. (2013) Murine hepatitis virus nsp4 N258T mutants are not temperature-sensitive. Virology 435:210-3
Gadlage, Mark J; Sparks, Jennifer S; Beachboard, Dia C et al. (2010) Murine hepatitis virus nonstructural protein 4 regulates virus-induced membrane modifications and replication complex function. J Virol 84:280-90
Graham, Rachel L; Sparks, Jennifer S; Eckerle, Lance D et al. (2008) SARS coronavirus replicase proteins in pathogenesis. Virus Res 133:88-100
Sparks, Jennifer S; Donaldson, Eric F; Lu, Xiaotao et al. (2008) A novel mutation in murine hepatitis virus nsp5, the viral 3C-like proteinase, causes temperature-sensitive defects in viral growth and protein processing. J Virol 82:5999-6008
Zhao, Zijiang; Thackray, Larissa B; Miller, Brian C et al. (2007) Coronavirus replication does not require the autophagy gene ATG5. Autophagy 3:581-5
Sparks, Jennifer S; Lu, Xiaotao; Denison, Mark R (2007) Genetic analysis of Murine hepatitis virus nsp4 in virus replication. J Virol 81:12554-63
Brockway, Sarah M; Lu, Xiao Tao; Peters, Timothy R et al. (2004) Intracellular localization and protein interactions of the gene 1 protein p28 during mouse hepatitis virus replication. J Virol 78:11551-62

Showing the most recent 10 out of 13 publications