Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI050105-02
Application #
6686394
Study Section
Immunobiology Study Section (IMB)
Program Officer
Macchiarini, Francesca
Project Start
2002-12-15
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$292,727
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Pathology
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Klein, Ludger; Kyewski, Bruno; Allen, Paul M et al. (2014) Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see). Nat Rev Immunol 14:377-91
McCaughtry, Tom M; Baldwin, Troy A; Wilken, Matthew S et al. (2008) Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla. J Exp Med 205:2575-84
McCaughtry, Tom M; Wilken, Matthew S; Hogquist, Kristin A (2007) Thymic emigration revisited. J Exp Med 204:2513-20
Baldwin, Troy A; Hogquist, Kristin A (2007) Transcriptional analysis of clonal deletion in vivo. J Immunol 179:837-44
Baldwin, Troy A; Sandau, Michelle M; Jameson, Stephen C et al. (2005) The timing of TCR alpha expression critically influences T cell development and selection. J Exp Med 202:111-21
Mayerova, Dita; Hogquist, Kristin A (2004) Central tolerance to self-antigen expressed by cortical epithelial cells. J Immunol 172:851-6
Mayerova, Dita; Parke, Evan A; Bursch, Laura S et al. (2004) Langerhans cells activate naive self-antigen-specific CD8 T cells in the steady state. Immunity 21:391-400
Holman, Philmore O; Walsh, Elizabeth R; Hogquist, Kristin A (2003) The central tolerance response to male antigen in normal mice is deletion and not receptor editing. J Immunol 171:4048-53