Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI051346-02
Application #
6689006
Study Section
Special Emphasis Panel (ZRG1-SSS-F (01))
Program Officer
Chiodetti, Lynda
Project Start
2003-01-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$262,210
Indirect Cost
Name
Oregon Health and Science University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Raué, Hans-Peter; Slifka, Mark K (2009) CD8+ T cell immunodominance shifts during the early stages of acute LCMV infection independently from functional avidity maturation. Virology 390:197-204
Koguchi, Yoshinobu; Thauland, Timothy J; Slifka, Mark K et al. (2007) Preformed CD40 ligand exists in secretory lysosomes in effector and memory CD4+ T cells and is quickly expressed on the cell surface in an antigen-specific manner. Blood 110:2520-7
Raue, Hans-Peter; Slifka, Mark K (2007) Pivotal advance: CTLA-4+ T cells exhibit normal antiviral functions during acute viral infection. J Leukoc Biol 81:1165-75
Beadling, Carol; Slifka, Mark K (2006) Regulation of innate and adaptive immune responses by the related cytokines IL-12, IL-23, and IL-27. Arch Immunol Ther Exp (Warsz) 54:15-24
Beadling, Carol; Slifka, Mark K (2004) How do viral infections predispose patients to bacterial infections? Curr Opin Infect Dis 17:185-91
Gold, Marielle C; Munks, Michael W; Wagner, Markus et al. (2004) Murine cytomegalovirus interference with antigen presentation has little effect on the size or the effector memory phenotype of the CD8 T cell response. J Immunol 172:6944-53
Whitton, J Lindsay; Slifka, Mark K; Liu, Fei et al. (2004) The regulation and maturation of antiviral immune responses. Adv Virus Res 63:181-238
Hammarlund, Erika; Lewis, Matthew W; Hansen, Scott G et al. (2003) Duration of antiviral immunity after smallpox vaccination. Nat Med 9:1131-7