Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI053091-02
Application #
6688994
Study Section
Allergy and Immunology Study Section (ALY)
Program Officer
Mallia, Conrad M
Project Start
2002-12-15
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$304,000
Indirect Cost
Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
McGargill, Maureen A; Choy, Carmen; Wen, Ben G et al. (2008) Drak2 regulates the survival of activated T cells and is required for organ-specific autoimmune disease. J Immunol 181:7593-605
Wang, Shuhui; Welte, Thomas; McGargill, Maureen et al. (2008) Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis. J Immunol 181:2084-91
Friedrich, Monica L; Wen, Ben G; Bain, Gretchen et al. (2005) DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection. Int Immunol 17:1379-90
McGargill, Maureen A; Wen, Ben G; Walsh, Craig M et al. (2004) A deficiency in Drak2 results in a T cell hypersensitivity and an unexpected resistance to autoimmunity. Immunity 21:781-91