Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI053666-02
Application #
6690043
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Program Officer
Kehn, Patricia J
Project Start
2002-12-15
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$327,750
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Jindra, P T; Tripathi, S; Tian, C et al. (2013) Tolerance to MHC class II disparate allografts through genetic modification of bone marrow. Gene Ther 20:478-86
Tian, Chaorui; Yuan, Xueli; Jindra, Peter T et al. (2010) Induction of transplantation tolerance to fully mismatched cardiac allografts by T cell mediated delivery of alloantigen. Clin Immunol 136:174-87
Jindra, Peter T; Bagley, Jessamyn; Godwin, Jonathan G et al. (2010) Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten. J Immunol 185:990-7
Tian, Chaorui; Yuan, Xueli; Bagley, Jessamyn et al. (2008) Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells. Clin Immunol 127:130-7
Tian, C; Bagley, J; Iacomini, J (2007) Homeostatic expansion permits T cells to re-enter the thymus and deliver antigen in a tolerogenic fashion. Am J Transplant 7:1934-41
Bagley, Jessamyn; Singh, Gyanesh; Iacomini, John (2007) Regulation of oxidative stress responses by ataxia-telangiectasia mutated is required for T cell proliferation. J Immunol 178:4757-63
Bagley, Jessamyn; Tian, Chaorui; Iacomini, John (2007) New approaches to the prevention of organ allograft rejection and tolerance induction. Transplantation 84:S38-41
Iacomini, John; Sayegh, Mohamed H (2006) Measuring T cell alloreactivity to predict kidney transplant outcomes: are we there yet? J Am Soc Nephrol 17:328-30