Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI054232-02
Application #
6768711
Study Section
AIDS and Related Research 8 (AARR)
Program Officer
Plaeger, Susan F
Project Start
2003-07-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$661,455
Indirect Cost

  Institution

Name
University of Minnesota Twin Cities
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Estes, Jacob D; Reilly, Cavan; Trubey, Charles M et al. (2015) Antifibrotic therapy in simian immunodeficiency virus infection preserves CD4+ T-cell populations and improves immune reconstitution with antiretroviral therapy. J Infect Dis 211:744-54
Zeng, Ming; Haase, Ashley T; Schacker, Timothy W (2012) Lymphoid tissue structure and HIV-1 infection: life or death for T cells. Trends Immunol 33:306-14
Schacker, Timothy W; Bosch, Ronald J; Bennett, Kara et al. (2010) Measurement of naive CD4 cells reliably predicts potential for immune reconstitution in HIV. J Acquir Immune Defic Syndr 54:59-62
Estes, Jacob; Baker, Jason V; Brenchley, Jason M et al. (2008) Collagen deposition limits immune reconstitution in the gut. J Infect Dis 198:456-64
Estes, Jacob D; Haase, Ashley T; Schacker, Timothy W (2008) The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche. Semin Immunol 20:181-6
Brenchley, J M; Knox, K S; Asher, A I et al. (2008) High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage. Mucosal Immunol 1:49-58
Brenchley, Jason M; Paiardini, Mirko; Knox, Kenneth S et al. (2008) Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112:2826-35
Estes, Jacob D; Wietgrefe, Stephen; Schacker, Timothy et al. (2007) Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection. J Infect Dis 195:551-61
Skarda, David E; Taylor, Jodie H; Chipman, Jeffrey G et al. (2007) Inguinal lymph node biopsy in patients infected with the human immunodeficiency virus is safe. Surg Infect (Larchmt) 8:173-8
Schacker, Timothy W; Brenchley, Jason M; Beilman, Gregory J et al. (2006) Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection. Clin Vaccine Immunol 13:556-60

Showing the most recent 10 out of 12 publications