Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI056016-02
Application #
6757195
Study Section
Immunobiology Study Section (IMB)
Program Officer
Macchiarini, Francesca
Project Start
2003-07-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$291,160
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Burbach, Brandon J; Srivastava, Rupa; Medeiros, Ricardo B et al. (2008) Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAP. J Immunol 181:4840-51
Zou, Liangxing; Mendez, Felipe; Martin-Orozco, Natalia et al. (2008) Defective positive selection results in T cell lymphopenia and increased autoimmune diabetes in ADAP-deficient BDC2.5-C57BL/6 mice. Eur J Immunol 38:986-94
Medeiros, Ricardo B; Burbach, Brandon J; Mueller, Kristen L et al. (2007) Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1. Science 316:754-8
Dluzniewska, Joanna; Zou, Liangxing; Harmon, Ian R et al. (2007) Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis. Eur J Immunol 37:3208-19
Mueller, Kristen L; Thomas, Molly S; Burbach, Brandon J et al. (2007) Adhesion and degranulation-promoting adapter protein (ADAP) positively regulates T cell sensitivity to antigen and T cell survival. J Immunol 179:3559-69