Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI056094-02
Application #
6799301
Study Section
Special Emphasis Panel (ZRG1-SSS-F (01))
Program Officer
Gondre-Lewis, Timothy A
Project Start
2003-09-15
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$319,726
Indirect Cost
Name
Pennsylvania State University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
Norbury, Christopher C (2016) Defining cross presentation for a wider audience. Curr Opin Immunol 40:110-6
Sei, Janet J; Haskett, Scott; Kaminsky, Lauren W et al. (2015) Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation. PLoS Pathog 11:e1004941
Kaminsky, Lauren W; Sei, Janet J; Parekh, Nikhil J et al. (2015) Redundant Function of Plasmacytoid and Conventional Dendritic Cells Is Required To Survive a Natural Virus Infection. J Virol 89:9974-85
Heipertz, Erica L; Davies, Michael L; Lin, Eugene et al. (2014) Prolonged antigen presentation following an acute virus infection requires direct and then cross-presentation. J Immunol 193:4169-77
Davies, Michael L; Sei, Janet J; Siciliano, Nicholas A et al. (2014) MyD88-dependent immunity to a natural model of vaccinia virus infection does not involve Toll-like receptor 2. J Virol 88:3557-67
Hunzeker, John T; Elftman, Michael D; Mellinger, Jennifer C et al. (2011) A marked reduction in priming of cytotoxic CD8+ T cells mediated by stress-induced glucocorticoids involves multiple deficiencies in cross-presentation by dendritic cells. J Immunol 186:183-94
Fischer, Matthew A; Davies, Michael L; Reider, Irene E et al. (2011) CD11b?, Ly6G? cells produce type I interferon and exhibit tissue protective properties following peripheral virus infection. PLoS Pathog 7:e1002374
Elftman, Michael D; Hunzeker, John T; Mellinger, Jennifer C et al. (2010) Stress-induced glucocorticoids at the earliest stages of herpes simplex virus-1 infection suppress subsequent antiviral immunity, implicating impaired dendritic cell function. J Immunol 184:1867-75
Schell, Amanda M; Granger, Erica L; Koczot, Frank et al. (2010) Dendritic cell migration limits the duration of CD8+ T-cell priming to peripheral viral antigen. J Virol 84:3586-94
Tewalt, Eric F; Grant, Jean M; Granger, Erica L et al. (2009) Viral sequestration of antigen subverts cross presentation to CD8(+) T cells. PLoS Pathog 5:e1000457

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