Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI056129-02
Application #
6761802
Study Section
Immunobiology Study Section (IMB)
Program Officer
Mallia, Conrad M
Project Start
2003-07-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$346,500
Indirect Cost
Name
Oklahoma Medical Research Foundation
Department
Type
DUNS #
077333797
City
Oklahoma City
State
OK
Country
United States
Zip Code
73104
Zhao, Ying; Ling, Flora; Griffin, Timothy M et al. (2014) Up-regulation of the Sirtuin 1 (Sirt1) and peroxisome proliferator-activated receptor ? coactivator-1? (PGC-1?) genes in white adipose tissue of Id1 protein-deficient mice: implications in the protection against diet and age-induced glucose intolerance. J Biol Chem 289:29112-22
Liu, Chen; Wang, Hong-Cheng; Yu, Sen et al. (2014) Id1 expression promotes T regulatory cell differentiation by facilitating TCR costimulation. J Immunol 193:663-672
Liu, Chen; Jin, Rong; Wang, Hong-Cheng et al. (2013) Id1 expression promotes peripheral CD4+ T cell proliferation and survival upon TCR activation without co-stimulation. Biochem Biophys Res Commun 436:47-52
Zhao, Ying; Ling, Flora; Wang, Hong-Cheng et al. (2013) Chronic TLR signaling impairs the long-term repopulating potential of hematopoietic stem cells of wild type but not Id1 deficient mice. PLoS One 8:e55552
Hu, Taishan; Wang, Hongcheng; Simmons, Amie et al. (2013) Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets. J Immunol 191:5065-73
Zhang, Ping; Zhao, Ying; Sun, Xiao-Hong (2013) Notch-regulated periphery B cell differentiation involves suppression of E protein function. J Immunol 191:726-36
Wang, Hong-Cheng; Peng, Vincent; Zhao, Ying et al. (2012) Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice. PLoS One 7:e32944
Wu, Wei; Sun, Xiao-Hong (2012) Janus kinase 3: the controller and the controlled. Acta Biochim Biophys Sin (Shanghai) 44:187-96
Nie, Lei; Zhao, Ying; Wu, Wei et al. (2011) Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes. Cell Res 21:754-69
Wu, Wei; Sun, Xiao-Hong (2011) A mechanism underlying NOTCH-induced and ubiquitin-mediated JAK3 degradation. J Biol Chem 286:41153-62

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