Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI056484-02
Application #
6767828
Study Section
Special Emphasis Panel (ZRG1-EVR (04))
Program Officer
Wali, Tonu M
Project Start
2003-07-01
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$404,790
Indirect Cost

  Institution

Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Public Health
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Tundup, Smanla; Srivastava, Leena; Norberg, Thomas et al. (2015) A Neoglycoconjugate Containing the Human Milk Sugar LNFPIII Drives Anti-Inflammatory Activation of Antigen Presenting Cells in a CD14 Dependent Pathway. PLoS One 10:e0137495
Marrache, Sean; Tundup, Smanla; Harn, Donald A et al. (2015) Ex vivo generation of functional immune cells by mitochondria-targeted photosensitization of cancer cells. Methods Mol Biol 1265:113-22
Tundup, Smanla; Srivastava, Leena; Nagy, Tamas et al. (2014) CD14 influences host immune responses and alternative activation of macrophages during Schistosoma mansoni infection. Infect Immun 82:3240-51
Srivastava, Leena; Tundup, Smanla; Choi, Beak-San et al. (2014) Immunomodulatory glycan lacto-N-fucopentaose III requires clathrin-mediated endocytosis to induce alternative activation of antigen-presenting cells. Infect Immun 82:1891-903
Pathak, Rakesh K; Marrache, Sean; Harn, Donald A et al. (2014) Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate. ACS Chem Biol 9:1178-87
Marrache, Sean; Tundup, Smanla; Harn, Donald A et al. (2013) Ex vivo programming of dendritic cells by mitochondria-targeted nanoparticles to produce interferon-gamma for cancer immunotherapy. ACS Nano 7:7392-402
Marrache, Sean; Choi, Joshua H; Tundup, Smanla et al. (2013) Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer. Integr Biol (Camb) 5:215-23
Bhargava, Prerna; Li, Changlin; Stanya, Kristopher J et al. (2012) Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways. Nat Med 18:1665-72
Tundup, Smanla; Srivastava, Leena; Harn Jr, Donald A (2012) Polarization of host immune responses by helminth-expressed glycans. Ann N Y Acad Sci 1253:E1-E13
Wang, Yang; Da'Dara, Akram A; Thomas, Paul G et al. (2010) Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses. Immunology 129:406-17

Showing the most recent 10 out of 14 publications