Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases (NIADDK)
Type
Research Project (R01)
Project #
3R01AM018844-09S1
Application #
3151165
Study Section
Nutrition Study Section (NTN)
Project Start
1976-05-01
Project End
1985-09-29
Budget Start
1985-05-01
Budget End
1985-09-29
Support Year
9
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Ohio State University
Department
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Careaga, M M; Sprecher, H (1987) Metabolism of 8,11,14,17-eicosatetraenoic acid by human platelet lipoxygenase and cyclooxygenase. Biochim Biophys Acta 920:94-101
Oliw, E H; Sprecher, H; Hamberg, M (1986) Isolation of two novel E prostaglandins in human seminal fluid. J Biol Chem 261:2675-83
Sprecher, H (1986) The metabolism of (n-3) and (n-6) fatty acids and their oxygenation by platelet cyclooxygenase and lipoxygenase. Prog Lipid Res 25:19-28
Sprecher, H; Careaga, M M (1986) Metabolism of (n-6) and (n-3) polyunsaturated fatty acids by human platelets. Prostaglandins Leukot Med 23:129-34
Meijer, L; Brash, A R; Bryant, R W et al. (1986) Stereospecific induction of starfish oocyte maturation by (8R)-hydroxyeicosatetraenoic acid. J Biol Chem 261:17040-7
Evans, R W; Sprecher, H (1985) Total synthesis and spectral characterization of 5,8,14-icosatrienoic acid and 5,11,14-icosatrienoic acid and their acetylenic analogues. Chem Phys Lipids 38:327-42
Evans, R W; Sprecher, H (1985) Metabolism of icosa-5,11,14-trienoic acid in human platelets and the inhibition of arachidonic acid metabolism in human platelets by icosa-5,8,14-triynoic and icosa-5,11,14-triynoic acids. Prostaglandins 29:431-41
Weiner, T W; Sprecher, H (1985) 22-Carbon polyenoic acids. Incorporation into platelet phospholipids and the synthesis of these acids from 20-carbon polyenoic acid precursors by intact platelets. J Biol Chem 260:6032-8
VanRollins, M; Horrocks, L; Sprecher, H (1985) Metabolism of 7,10,13,16-docosatetraenoic acid to dihomo-thromboxane, 14-hydroxy-7,10,12-nonadecatrienoic acid and hydroxy fatty acids by human platelets. Biochim Biophys Acta 833:272-80
Milks, M M; Sprecher, H (1985) Metabolism of 4,7,10,13,16-docosapentaenoic acid by human platelet cyclooxygenase and lipoxygenase. Biochim Biophys Acta 835:29-35