Much controversy exists over the significance of the knee laxity exam. This has resulted, in part, from a lack of knowledge as to the restraining functions of the various ligaments and capsular structures. During the first grant period we measured the ligament restraints to the so-called """"""""straight instabilites."""""""" These are anterior-posterior drawer and straight medial-lateral opening. In the proposed renewal period we will study the restraining action of the ligaments to the rotatory instabilities. These instabilities involve combined rotational and translational knee motion. The rotatory motion is that associated with axial tibial rotation. The translations are anterior-posterior drawer and medial-lateral shifting of the tibia. We propose to address the problem of defining the significance of rotatory laxities, with regard to injury, by applying three distinct methodologies. These are described below in separate projects. They include: 1) Measuring the three-dimensional restraining forces of the ligaments to well defined and reproducible rotations of the tibia, 2) measuring the three-dimensional motions which occur during the various clinical exams for rotatory instability along with the changes in motion associated with specific ligament injuries, and 3) synthesizing these results on ligament function into a mathematical model capable of testing our understanding of both the effects of the various individual factors (i.e., ligaments, joint geometry, compressive forces, etc.) and their complex interactions.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases (NIADDK)
Type
Research Project (R01)
Project #
5R01AM021172-08
Application #
3151349
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1978-01-01
Project End
1988-12-31
Budget Start
1985-01-01
Budget End
1985-12-31
Support Year
8
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Butler, D L (1989) Kappa Delta Award paper. Anterior cruciate ligament: its normal response and replacement. J Orthop Res 7:910-21
Butler, D L; Grood, E S; Noyes, F R et al. (1989) Mechanical properties of primate vascularized vs. nonvascularized patellar tendon grafts;changes over time. J Orthop Res 7:68-79
Holden, J P; Grood, E S; Butler, D L et al. (1988) Biomechanics of fascia lata ligament replacements: early postoperative changes in the goat. J Orthop Res 6:639-47
Noyes, F R; Grood, E S (1987) Classification of ligament injuries: why an anterolateral laxity or anteromedial laxity is not a diagnostic entity. Instr Course Lect 36:185-200
Jackson, D W; Grood, E S; Arnoczky, S P et al. (1987) Freeze dried anterior cruciate ligament allografts. Preliminary studies in a goat model. Am J Sports Med 15:295-303
Hefzy, M S; Grood, E S (1986) Sensitivity of insertion locations on length patterns of anterior cruciate ligament fibers. J Biomech Eng 108:73-82
Butler, D L; Grood, E S; Noyes, F R et al. (1985) On the interpretation of our anterior cruciate ligament data. Clin Orthop Relat Res :26-34
Noyes, F R; McGinniss, G H; Grood, E S (1985) The variable functional disability of the anterior cruciate ligament-deficient knee. Orthop Clin North Am 16:47-67