Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR032372-12
Application #
2078834
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1983-07-01
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
12
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Orthopedics
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Gupta, P; Oegema Jr, T R; Brazil, J J et al. (2000) Human LTC-IC can be maintained for at least 5 weeks in vitro when interleukin-3 and a single chemokine are combined with O-sulfated heparan sulfates: requirement for optimal binding interactions of heparan sulfate with early-acting cytokines and matrix pr Blood 95:147-55
Gupta, P; Oegema Jr, T R; Brazil, J J et al. (1998) Structurally specific heparan sulfates support primitive human hematopoiesis by formation of a multimolecular stem cell niche. Blood 92:4641-51
Sundaram, L; Deloria, L B; Oegema Jr, T R (1997) Mercuric salt-catalyzed removal of unsaturated glucuronic acid from chondroitinase-treated proteochondroitin sulfate. Arch Biochem Biophys 338:213-9
Drake, S L; Klein, D J; Mickelson, D J et al. (1992) Cell surface phosphatidylinositol-anchored heparan sulfate proteoglycan initiates mouse melanoma cell adhesion to a fibronectin-derived, heparin-binding synthetic peptide. J Cell Biol 117:1331-41
Faassen, A E; Schrager, J A; Klein, D J et al. (1992) A cell surface chondroitin sulfate proteoglycan, immunologically related to CD44, is involved in type I collagen-mediated melanoma cell motility and invasion. J Cell Biol 116:521-31
Platt, J L; Trescony, P; Lindman, B et al. (1990) Heparin and heparan sulfate delimit nephron formation in fetal metanephric kidneys. Dev Biol 139:338-48
Klein, D J; Oegema Jr, T R; Brown, D M (1989) Release of glomerular heparan-35SO4 proteoglycan by heparin from glomeruli of streptozocin-induced diabetic rats. Diabetes 38:130-9
Trescony, P V; Oegema Jr, T R; Farnam, B J et al. (1989) Analysis of heparan sulfate from the Engelbreth-Holm-Swarm (EHS) tumor. Connect Tissue Res 19:219-42
Klein, D J; Brown, D M; Oegema, T R et al. (1988) Glomerular basement membrane proteoglycans are derived from a large precursor. J Cell Biol 106:963-70