Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR033713-12
Application #
2078937
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1985-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Sasaki, Takahiro; Iwata, Satoshi; Okano, Hirotaka James et al. (2005) Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats: possible involvement of Nedd9 in the differentiation of neurons after ischemia. Stroke 36:2457-62
Kobayashi, H; Hosono, O; Iwata, S et al. (2004) The tetraspanin CD9 is preferentially expressed on the human CD4(+)CD45RA+ naive T cell population and is involved in T cell activation. Clin Exp Immunol 137:101-8
Ohnuma, Kei; Yamochi, Tadanori; Uchiyama, Masahiko et al. (2004) CD26 up-regulates expression of CD86 on antigen-presenting cells by means of caveolin-1. Proc Natl Acad Sci U S A 101:14186-91
Kobayashi, Seiji; Ohnuma, Kei; Uchiyama, Masahiko et al. (2004) Association of CD26 with CD45RA outside lipid rafts attenuates cord blood T-cell activation. Blood 103:1002-10
Miyake-Nishijima, Rikako; Iwata, Satoshi; Saijo, Shinobu et al. (2003) Role of Crk-associated substrate lymphocyte type in the pathophysiology of rheumatoid arthritis in tax transgenic mice and in humans. Arthritis Rheum 48:1890-900
Sato, K; Aytac, U; Yamochi, T et al. (2003) CD26/dipeptidyl peptidase IV enhances expression of topoisomerase II alpha and sensitivity to apoptosis induced by topoisomerase II inhibitors. Br J Cancer 89:1366-74
Ishii, Tomonori; Ohnuma, Kei; Murakami, Akikazu et al. (2003) SS-A/Ro52, an autoantigen involved in CD28-mediated IL-2 production. J Immunol 170:3653-61
Iwata, Satoshi; Kobayashi, Hiroshi; Miyake-Nishijima, Rikako et al. (2002) Distinctive signaling pathways through CD82 and beta1 integrins in human T cells. Eur J Immunol 32:1328-37
Dang, N H; Morimoto, C (2002) CD26: an expanding role in immune regulation and cancer. Histol Histopathol 17:1213-26
Ohnuma, Kei; Ishii, Tomonori; Iwata, Satoshi et al. (2002) G1/S cell cycle arrest provoked in human T cells by antibody to CD26. Immunology 107:325-33

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