Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR039571-06
Application #
2079588
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1989-08-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Grey, A; Chen, Y; Paliwal, I et al. (2000) Evidence for a functional association between phosphatidylinositol 3-kinase and c-src in the spreading response of osteoclasts to colony-stimulating factor-1. Endocrinology 141:2129-38
Kerstetter, J E; Mitnick, M E; Gundberg, C M et al. (1999) Changes in bone turnover in young women consuming different levels of dietary protein. J Clin Endocrinol Metab 84:1052-5
Yao, G Q; Sun, B h; Hammond, E E et al. (1998) The cell-surface form of colony-stimulating factor-1 is regulated by osteotropic agents and supports formation of multinucleated osteoclast-like cells. J Biol Chem 273:4119-28
Masiukiewicz, U S; Insogna, K L (1998) The role of parathyroid hormone in the pathogenesis, prevention and treatment of postmenopausal osteoporosis. Aging (Milano) 10:232-9
Kerstetter, J E; Caseria, D M; Mitnick, M E et al. (1997) Increased circulating concentrations of parathyroid hormone in healthy, young women consuming a protein-restricted diet. Am J Clin Nutr 66:1188-96
Sun, B H; Mitnick, M; Eielson, C et al. (1997) Parathyroid hormone increases circulating levels of fibronectin in vivo: modulating effect of ovariectomy. Endocrinology 138:3918-24
Insogna, K; Tanaka, S; Neff, L et al. (1997) Role of c-Src in cellular events associated with colony-stimulating factor-1-induced spreading in osteoclasts. Mol Reprod Dev 46:104-8
Grey, A; Mitnick, M A; Shapses, S et al. (1996) Circulating levels of interleukin-6 and tumor necrosis factor-alpha are elevated in primary hyperparathyroidism and correlate with markers of bone resorption--a clinical research center study. J Clin Endocrinol Metab 81:3450-4
Weir, E C; Lowik, C W; Paliwal, I et al. (1996) Colony stimulating factor-1 plays a role in osteoclast formation and function in bone resorption induced by parathyroid hormone and parathyroid hormone-related protein. J Bone Miner Res 11:1474-81
Kaplan, D L; Eielson, C M; Horowitz, M C et al. (1996) Tumor necrosis factor-alpha induces transcription of the colony-stimulating factor-1 gene in murine osteoblasts. J Cell Physiol 168:199-208

Showing the most recent 10 out of 17 publications