Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
2R01AR040765-05A1
Application #
2006218
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1991-08-01
Project End
2000-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Jiang, S; Xia, D; Samols, D (2006) Expression of rabbit C-reactive protein in transgenic mice inhibits development of antigen-induced arthritis. Scand J Rheumatol 35:351-5
Black, Steven; Agrawal, Alok; Samols, David (2003) The phosphocholine and the polycation-binding sites on rabbit C-reactive protein are structurally and functionally distinct. Mol Immunol 39:1045-54
Xia, D; Samols, D (1997) Transgenic mice expressing rabbit C-reactive protein are resistant to endotoxemia. Proc Natl Acad Sci U S A 94:2575-80
Zhang, D; Sun, M; Samols, D et al. (1996) STAT3 participates in transcriptional activation of the C-reactive protein gene by interleukin-6. J Biol Chem 271:9503-9
Zhang, D; Xia, D; Samols, D (1995) Generation of deletion mutants by partial digestion. Biotechniques 18:750-2
Lin, C S; Xia, D; Yun, J S et al. (1995) Expression of rabbit C-reactive protein in transgenic mice. Immunol Cell Biol 73:521-31
Renia, L; Rodrigues, M M; Nussenzweig, V (1994) Intrasplenic immunization with infected hepatocytes: a mouse model for studying protective immunity against malaria pre-erythrocytic stage. Immunology 82:164-8
Renia, L; Xia, D; Samols, D et al. (1993) Transgenic mice expressing C-reactive protein are susceptible to infection with Plasmodium yoelii sporozoites. Infect Immun 61:348-9