Muscle Myosin Cross Bridge Kinetics - Calcium Dependence

Kerrick, Wallace Glenn Lee

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: Research Project (R01)
• Project #: 1R01AR040906-01A5
• Application #: 2080329
• Study Section: Experimental Cardiovascular Sciences Study Section (ECS)
• Project Start: 1996-07-20
• Project End: 2001-06-30
• Budget Start: 1996-07-20
• Budget End: 1997-06-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of Miami School of Medicine
• Department: Physiology
• Type: Schools of Medicine
• City: Miami
• State: FL
• Country: United States
• Zip Code: 33146

Publications

Kerrick, W Glenn L; Xu, Yuanyuan (2004) Inorganic phosphate affects the pCa-force relationship more than the pCa-ATPase by increasing the rate of dissociation of force generating cross-bridges in skinned fibers from both EDL and soleus muscles of the rat. J Muscle Res Cell Motil 25:107-17

Miller, T; Szczesna, D; Housmans, P R et al. (2001) Abnormal contractile function in transgenic mice expressing a familial hypertrophic cardiomyopathy-linked troponin T (I79N) mutation. J Biol Chem 276:3743-55

Allen, K; Xu, Y Y; Kerrick, W G (2000) Ca(2+) measurements in skinned cardiac fibers: effects of Mg(2+) on Ca(2+) activation of force and fiber ATPase. J Appl Physiol 88:180-5