Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR042015-03
Application #
2081208
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1994-08-15
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Holderbaum, D; Haqqi, T M; Moskowitz, R W (1999) Genetics and osteoarthritis: exposing the iceberg. Arthritis Rheum 42:397-405
Bleasel, J F; Poole, A R; Heinegard, D et al. (1999) Changes in serum cartilage marker levels indicate altered cartilage metabolism in families with the osteoarthritis-related type II collagen gene COL2A1 mutation. Arthritis Rheum 42:39-45
Bleasel, J F; Holderbaum, D; Brancolini, V et al. (1998) Five families with arginine 519-cysteine mutation in COL2A1: evidence for three distinct founders. Hum Mutat 12:172-6
Bleasel, J F; Holderbaum, D; Mallock, V et al. (1996) Hereditary osteoarthritis with mild spondyloepiphyseal dysplasia--are there ""hot spots"" on COL2A1? J Rheumatol 23:1594-8
Bleasel, J F; Holderbaum, D; Brancolini, V et al. (1996) Arg519-Cys mutation in COL2A1: evidence for multiple founders. Ann N Y Acad Sci 785:215-8