Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
1R01AR042732-01A3
Application #
2082174
Study Section
Pathology A Study Section (PTHA)
Project Start
1996-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118
Rauch, J; Subang, R; D'Agnillo, P et al. (2000) Apoptosis and the antiphospholipid syndrome. J Autoimmun 15:231-5
Koh, J S; Wang, Z; Levine, J S (2000) Cytokine dysregulation induced by apoptotic cells is a shared characteristic of murine lupus. J Immunol 165:4190-201
Subang, R; Levine, J S; Janoff, A S et al. (2000) Phospholipid-bound beta 2-glycoprotein I induces the production of anti-phospholipid antibodies. J Autoimmun 15:21-32
Levine, J S; Koh, J S; Subang, R et al. (1999) Apoptotic cells as immunogen and antigen in the antiphospholipid syndrome. Exp Mol Pathol 66:82-98
Levine, J S; Koh, J S (1999) The role of apoptosis in autoimmunity: immunogen, antigen, and accelerant. Semin Nephrol 19:34-47
Levine, J S; Koh, J S; Hartwell, D et al. (1998) Adhesion elicits an intrinsic defect in interleukin-1 expression by macrophages from autoimmune-prone MRL mice. J Autoimmun 11:141-50
Lieberthal, W; Menza, S A; Levine, J S (1998) Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells. Am J Physiol 274:F315-27
Levine, J S; Subang, R; Koh, J S et al. (1998) Induction of anti-phospholipid autoantibodies by beta2-glycoprotein I bound to apoptotic thymocytes. J Autoimmun 11:413-24
Levine, J S; Koh, J S; Triaca, V et al. (1997) Lysophosphatidic acid: a novel growth and survival factor for renal proximal tubular cells. Am J Physiol 273:F575-85
Koh, J S; Levine, J S (1997) Apoptosis and autoimmunity. Curr Opin Nephrol Hypertens 6:259-66

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