Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
1R01AR043470-01A2
Application #
2083183
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Barnes-Jewish Hospital
Department
Type
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63110
Di Benedetto, Adriana; Watkins, Marcus; Grimston, Susan et al. (2010) N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms. J Cell Sci 123:2640-8
Salazar, Valerie S; Mbalaviele, Gabriel; Civitelli, Roberto (2008) The pro-osteogenic action of beta-catenin requires interaction with BMP signaling, but not Tcf/Lef transcriptional activity. J Cell Biochem 104:942-52
Mbalaviele, Gabriel; Shin, Chan Soo; Civitelli, Roberto (2006) Cell-cell adhesion and signaling through cadherins: connecting bone cells in their microenvironment. J Bone Miner Res 21:1821-7
Lai, Chung Fang; Cheng, Su-Li; Mbalaviele, Gabriel et al. (2006) Accentuated ovariectomy-induced bone loss and altered osteogenesis in heterozygous N-cadherin null mice. J Bone Miner Res 21:1897-906
Mbalaviele, Gabriel; Sheikh, Sharmin; Stains, Joseph P et al. (2005) Beta-catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation. J Cell Biochem 94:403-18
Stains, Joseph P; Civitelli, Roberto (2005) Cell-to-cell interactions in bone. Biochem Biophys Res Commun 328:721-7
Stains, Joseph P; Civitelli, Roberto (2005) Cell-cell interactions in regulating osteogenesis and osteoblast function. Birth Defects Res C Embryo Today 75:72-80
Castro, Charlles H M; Shin, Chan Soo; Stains, Joseph P et al. (2004) Targeted expression of a dominant-negative N-cadherin in vivo delays peak bone mass and increases adipogenesis. J Cell Sci 117:2853-64
Stains, Joseph P; Civitelli, Roberto (2003) Genomic approaches to identifying transcriptional regulators of osteoblast differentiation. Genome Biol 4:222
Jorgensen, Niklas R; Henriksen, Zanne; Sorensen, Ole H et al. (2002) Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors. J Biol Chem 277:7574-80

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