Analyses of load transmission through the lumbar spine are used to set safe limits for manual handling occupations to prevent low back pain and spinal injuries, and to guide rehabilitation of people with low back pain. This proposed research addresses the need for an improved method of analyzing forces transmitted through the human lumbar spine. This model will extend and improve previous models by the addition of three important elements: (1) the model will be truly three-dimensional with a realistic representation of muscular anatomy accounting for muscles which cross several motion segments. (2) It will respect the need for the lumbar spinal column to be loaded in a way which is structurally stable. (3) The spinal motion segments will be represented as realistic flexible structures. This model will be developed and validated through five logical steps by incorporating previously published data and using new modeling tools to examine plausible muscle force distributions and their contributions to spinal stability. Based on preliminary studies it is expected that the model will demonstrate how antagonistic muscles of the trunk are recruited. Preliminary results suggest that this may occur under three circumstances: (1) to maintain equilibrium at multiple levels of the spinal column; (2) to minimize muscles stresses, and (3) to maximize the structural stability of the spinal column. The model will also be used to show how different spinal postures and certain spinal injuries affect its stability and load-bearing capacity. The results will be used to identify loading conditions, spinal configurations and muscular activation patterns which may place the spine at risk for 'self-injury'. The methods developed in this study are also expected to have wider applicability to understanding human joint biomechanics and stability (e.g. the pinch grip between two digits.)

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
8R01AR044119-02
Application #
2083847
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1994-09-01
Project End
1998-08-31
Budget Start
1995-09-25
Budget End
1996-08-31
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Vermont & St Agric College
Department
Orthopedics
Type
Schools of Medicine
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Stokes, Ian A F; Gardner-Morse, Mack (2016) A database of lumbar spinal mechanical behavior for validation of spinal analytical models. J Biomech 49:780-785
Stokes, Ian A F (2007) Analysis and simulation of progressive adolescent scoliosis by biomechanical growth modulation. Eur Spine J 16:1621-8
Stokes, Ian A F; Fox, James R; Henry, Sharon M (2006) Trunk muscular activation patterns and responses to transient force perturbation in persons with self-reported low back pain. Eur Spine J 15:658-67
Stokes, Ian A F (2005) Relationships of EMG to effort in the trunk under isometric conditions: force-increasing and decreasing effects and temporal delays. Clin Biomech (Bristol, Avon) 20:9-15
Gardner-Morse, Mack G; Stokes, Ian A F (2004) Structural behavior of human lumbar spinal motion segments. J Biomech 37:205-12
Stokes, Ian A F; Gardner-Morse, Mack (2004) Muscle activation strategies and symmetry of spinal loading in the lumbar spine with scoliosis. Spine (Phila Pa 1976) 29:2103-7
Gardner-Morse, Mack G; Stokes, Ian A (2003) Physiological axial compressive preloads increase motion segment stiffness, linearity and hysteresis in all six degrees of freedom for small displacements about the neutral posture. J Orthop Res 21:547-52
Stokes, Ian A F; Gardner-Morse, Mack (2003) Spinal stiffness increases with axial load: another stabilizing consequence of muscle action. J Electromyogr Kinesiol 13:397-402
Gardner-Morse, Mark G; Stokes, Ian A; Churchill, David et al. (2002) Motion segment stiffness measured without physiological levels of axial compressive preload underestimates the in vivo values in all six degrees of freedom. Stud Health Technol Inform 91:167-72
Stokes, Ian A; Gardner-Morse, Mack; Churchill, David et al. (2002) Measurement of a spinal motion segment stiffness matrix. J Biomech 35:517-21

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