Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
1R01AR044360-01
Application #
2006800
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1996-09-30
Project End
2000-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Han, Fei; Gilbert, James R; Harrison, Gerald et al. (2007) Transforming growth factor-beta1 regulates fibronectin isoform expression and splicing factor SRp40 expression during ATDC5 chondrogenic maturation. Exp Cell Res 313:1518-32
Zaka, Raihana; Stokes, David; Dion, Arnold S et al. (2006) P5L mutation in Ank results in an increase in extracellular inorganic pyrophosphate during proliferation and nonmineralizing hypertrophy in stably transduced ATDC5 cells. Arthritis Res Ther 8:R164
Han, Fei; Adams, Christopher S; Tao, Zhuliang et al. (2005) Transforming growth factor-beta1 (TGF-beta1) regulates ATDC5 chondrogenic differentiation and fibronectin isoform expression. J Cell Biochem 95:750-62
Williams, Charlene J (2003) Familial calcium pyrophosphate dihydrate deposition disease and the ANKH gene. Curr Opin Rheumatol 15:326-31
Williams, Charlene J; Pendleton, Adrian; Bonavita, Gina et al. (2003) Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease. Arthritis Rheum 48:2627-31
Pendleton, Adrian; Johnson, Michelle D; Hughes, Anne et al. (2002) Mutations in ANKH cause chondrocalcinosis. Am J Hum Genet 71:933-40
Andrew, L J; Brancolini, V; de la Pena, L S et al. (1999) Refinement of the chromosome 5p locus for familial calcium pyrophosphate dihydrate deposition disease. Am J Hum Genet 64:136-45
Rojas, K; Serrano de la Pena, L; Gallardo, T et al. (1999) Physical map and characterization of transcripts in the candidate interval for familial chondrocalcinosis at chromosome 5p15.1. Genomics 62:177-83
Marinescu, R C; Nyce, K; Serrano de la Pena, L et al. (1999) Exclusion of the gene for human cartilage intermediate layer protein in currently mapped calcium pyrophosphate dihydrate deposition syndromes. Arthritis Rheum 42:2139-44