Brain-computer interface (BCI) technology is currently the subject of intense research interest, as it holds the promise to assist numerous patients suffering from neuromuscular disorders and other systemic and brain diseases. BCI systems allow users to interact with their environment without muscular control, by sensing and decoding the user's thoughts. Noninvasive BCI uses electroencephalography (EEG) to sense user's cognitive states; in EEG, scalp electrodes sense small potential changes arising from underlying neural activity. The effectiveness of BCI, however, depends critically upon training the user's cognitive abilities: users must learn to produce reliable patterns of brain activity that the BCI can decode from its sensors. Some users are able to complete this training with relative ease, but for others the learning process is difficult and lengthy. Thus, methods that can improve training promise to greatly enhance the usefulness of BCI in most applications, benefiting the many patients who may be aided with BCI technology. Mind-body awareness training (MBAT) has shown large effects upon both cognitive abilities and brain activity. MBAT emphasizes meditation practice that focuses on body states, and it has been shown to enhance factors that are most critical for sensorimotor- rhythm-based BCI: sustained attention, motor imagery, and generation of rhythmic neural signals. The general goal of the proposed research is to investigate whether and how experience with MBAT can improve subjects' ability to learn and use a sensorimotor-rhythm-based BCI.
The specific aims of the proposed research are as follows:
Aim 1 : We will test whether MBAT training has significant impact on learning of BCI skills. We will study human subjects with various levels of MBAT experience and compare them with controls.
Aim 2 : We will use and further develop novel multimodal neuroimaging methods, along with extensive behavioral testing, to identify the neurocognitive components of MBAT that aid learning of BCI skills. Comprehensive analyses will combine imaging and neurocognitive results to identify brain regions responsible for the factors that produce improvement in BCI. The successful completion of the proposed research may allow MBAT training to become a best practice in BCI use, increasing BCI signal quality and reducing its training time. It will also better the understanding on how mind-body intervention works through innovative neuroimaging approaches. Understanding the neurocognitive basis of improvement may allow the production of enhanced training regimens, both with and without MBAT, including MBAT-like training specifically tailored to optimize BCI.

Public Health Relevance

The goal of the proposed research is to establish Mind-Body Awareness Training as a novel approach for improving learning of and performance with brain-computer interface. This represents an important novel application of mind-body awareness training to neurofeedback, which has a host of applications, including pain management, skill learning, and treatment of mental disorders. The proposed research will significantly enhance the brain-computer interface use through mind-body intervention, and thus will benefit numerous p atients including disabled patients to enhance control over their environment.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Research Project (R01)
Project #
5R01AT009263-06
Application #
9937649
Study Section
Neuroscience and Ophthalmic Imaging Technologies Study Section (NOIT)
Program Officer
Chen, Wen G
Project Start
2018-02-01
Project End
2021-05-31
Budget Start
2020-06-01
Budget End
2021-05-31
Support Year
6
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Carnegie-Mellon University
Department
Biomedical Engineering
Type
Biomed Engr/Col Engr/Engr Sta
DUNS #
052184116
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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