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Pace, Christopher J; Glick, Stanley D; Maisonneuve, Isabelle M et al. (2004) Novel iboga alkaloid congeners block nicotinic receptors and reduce drug self-administration. Eur J Pharmacol 492:159-67
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Kuehne, Martin E; He, Liwen; Jokiel, Patrick A et al. (2003) Synthesis and biological evaluation of 18-methoxycoronaridine congeners. Potential antiaddiction agents. J Med Chem 46:2716-30
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Kuehne, Martin E; Bornmann, William G; Marko, Istvan et al. (2003) Syntheses and biological evaluation of vinblastine congeners. Org Biomol Chem 1:2120-36
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Zhang, Wenjiang; Ramamoorthy, Yamini; Tyndale, Rachel F et al. (2003) Interaction of buprenorphine and its metabolite norbuprenorphine with cytochromes p450 in vitro. Drug Metab Dispos 31:768-72
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Zhang, Wenjiang; Ramamoorthy, Yamini; Tyndale, Rachel F et al. (2002) Metabolism of 18-methoxycoronaridine, an ibogaine analog, to 18-hydroxycoronaridine by genetically variable CYP2C19. Drug Metab Dispos 30:663-9
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Gruol, Donald J; King, Miranda N; Kuehne, Martin E (2002) Evidence for the locations of distinct steroid and Vinca alkaloid interaction domains within the murine mdr1b P-glycoprotein. Mol Pharmacol 62:1238-48
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Kuehne, M E; Dai, W; Li, Y L (2001) New ferrocenyl chiral auxiliary substituents for amines: applications to syntheses of mossambine and vinblastine. J Org Chem 66:1560-6
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Kuehne, M E; Qin, Y; Huot, A E et al. (2001) The syntheses of 16a'-homo-leurosidine and 16a'-homo-vinblastine. Generation of atropisomers. J Org Chem 66:5317-28
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Kuehne, M E; Cowen, S D; Xu, F et al. (2001) Syntheses of 5a'-homo-vinblastine and congeners designed to establish structural determinants for isolation of atropisomers. J Org Chem 66:5303-16
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Kuehne, M E; Li, Y L; Wei, C Q (2000) Biogenetic syntheses of kopsijasminilam and deoxykopsijasminilam. J Org Chem 65:6434-40
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Showing the most recent 10 out of 15 publications
