The concepts and methods developed in the context of an efficient synthesis of (plus or minus)-daunomycinone (see J. Am. Chem. Soc. 102, 5983 (1981)) are being extended to the preparation of analogs of Adriamycin and to other naturally occurring quinonoid systems.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA017631-11
Application #
3164757
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1978-06-01
Project End
1986-05-31
Budget Start
1985-06-01
Budget End
1986-05-31
Support Year
11
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Boston College
Department
Type
Schools of Arts and Sciences
DUNS #
045896339
City
Chestnut Hill
State
MA
Country
United States
Zip Code