This epidemiologic study has two components. The first involves screening of commonly used medicinal drugs for possible carcinogenic effects. The drugs dispensed to 143,000 subscribers to the Kaiser Foundation Health Plan in the years 1969-1973 have been stored in computer records. These subjects are followed up through Health Plan Records and subsequent incidence of cancer (each site and all sites) is determined for users of the drugs to be screened. The second component involves testing of hypotheses generated by the above screening analyses by detailed case-control studies involving the subjects' complete medical records.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA019939-09
Application #
3165219
Study Section
Epidemiology and Disease Control Subcommittee 3 (EDC)
Project Start
1982-08-01
Project End
1987-03-31
Budget Start
1985-04-01
Budget End
1986-03-31
Support Year
9
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Kaiser Foundation Research Institute
Department
Type
DUNS #
City
Oakland
State
CA
Country
United States
Zip Code
94612
Selby, J V; Friedman, G D; Collen, M F (1988) Sigmoidoscopy and mortality from colorectal cancer: the Kaiser Permanente Multiphasic Evaluation Study. J Clin Epidemiol 41:427-34
Selby, J V; Friedman, G D (1988) Epidemiologic evidence of an association between body iron stores and risk of cancer. Int J Cancer 41:677-82
Friedman, G D; Blaner, W S; Goodman, D S et al. (1986) Serum retinol and retinol-binding protein levels do not predict subsequent lung cancer. Am J Epidemiol 123:781-9
Sidney, S; Friedman, G D; Hiatt, R A (1986) Serum cholesterol and large bowel cancer. A case-control study. Am J Epidemiol 124:33-8
Friedman, G D (1986) Multiple myeloma: relation to propoxyphene and other drugs, radiation and occupation. Int J Epidemiol 15:424-6