Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA023272-06S1
Application #
3166097
Study Section
Experimental Therapeutics Subcommittee 2 (ET)
Project Start
1978-04-01
Project End
1985-08-31
Budget Start
1984-07-01
Budget End
1985-08-31
Support Year
6
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Hospitals
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Yang, L Y; Trujillo, J M; Siciliano, M J et al. (1993) Distinct P-glycoprotein expression in two subclones simultaneously selected from a human colon carcinoma cell line by cis-diamminedichloroplatinum (II). Int J Cancer 53:478-85
Yang, L Y; Trujillo, J M; Su, Y Z (1992) Further characterization of two distinct adriamycin-resistant sublines from LoVo human colon carcinoma cells. Anticancer Res 12:473-9
Trujillo, J M; Yang, L Y; Gercovich, G et al. (1991) Heterogeneous effects of interferon on antitumor agents' cytotoxicities to human colon carcinoma cell lines. Anticancer Res 11:439-44
Yang, L Y; Trujillo, J M (1990) Biological characterization of multidrug-resistant human colon carcinoma sublines induced/selected by two methods. Cancer Res 50:3218-25
Trujillo, J M; Yang, L Y; Gercovich, G et al. (1989) Metronidazole enhances the cytotoxic synergism produced by the combination of 1-beta-arabinofuranosylcytosine and cis-diamminedichloroplatinum. Anticancer Res 9:1751-6
Trujillo, J M; Yang, L Y (1989) Synergism of 1-beta-D-arabinofuranosylcytosine and cis-diamminedichloroplatinum in their lethal efficacies against seven established cancer cell lines of gastrointestinal origin. Anticancer Res 9:197-201
Perez-Soler, R; Yang, L Y; Drewinko, B et al. (1988) Increased cytotoxicity and reversal of resistance to cis-diamminedichloro-platinum(II) with entrapment of cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum (II) in multilamellar lipid vesicles. Cancer Res 48:4509-12
Drewinko, B; Yang, L Y (1988) The heterogenous cytotoxic response of colon cancer cells is unrelated to phenotypic differentiation characteristics. Anticancer Res 8:161-4
Alama, A; Nicolin, A; Conte, P F et al. (1987) Evaluation of growth fractions with monoclonal antibodies to human alpha-DNA polymerase. Cancer Res 47:1892-6
Drewinko, B; Moskwa, P; Reuben, J (1987) Expression of transferrin receptors is unrelated to proliferative status in cultured human colon cancer cells. Anticancer Res 7:139-41

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