Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA023770-12S1
Application #
3166233
Study Section
Immunobiology Study Section (IMB)
Project Start
1979-01-01
Project End
1992-03-31
Budget Start
1990-04-01
Budget End
1992-03-31
Support Year
12
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Whitmore, A C; Prowse, D M; Haughton, G et al. (1991) Ig isotype switching in B lymphocytes. The effect of T cell-derived interleukins, cytokines, cholera toxin, and antigen on isotype switch frequency of a cloned B cell lymphoma. Int Immunol 3:95-103
Pennell, C A; Maynard, E; Arnold, L W et al. (1990) High frequency expression of S107 VH genes by peritoneal B cells of B10.H-2aH-4bP/WTS mice. J Immunol 145:1592-7
Bishop, G A; Pennell, C A; Travis, W et al. (1990) Antibodies specific for Ig idiotype, but not isotype, can substitute for antigen to induce IgM secretion by a B cell clone. Int Immunol 2:285-90
Van Houten, N; Haughton, G (1990) Simultaneously arising Ly-1(CD5) B cell lymphomas have identical expressed IgH and kappa-genes but different nonproductive heavy chain rearrangements. J Immunol 144:745-51
Whitmore, A C; Prowse, D M; Arnold, L W et al. (1989) Ig isotype switching in B lymphocytes. A method for estimating isotype switch frequency in cloned B cell lymphomas. Int Immunol 1:532-9
Van Houten, N; Willoughby, P B; Arnold, L W et al. (1989) Early commitment to neoplasia in murine B- and T-cell lymphomas arising late in life. J Natl Cancer Inst 81:47-54
Pennell, C A; Sheehan, K M; Brodeur, P H et al. (1989) Organization and expression of VH gene families preferentially expressed by Ly-1+ (CD5) B cells. Eur J Immunol 19:2115-21
Mercolino, T J; Locke, A L; Afshari, A et al. (1989) Restricted immunoglobulin variable region gene usage by normal Ly-1 (CD5+) B cells that recognize phosphatidyl choline. J Exp Med 169:1869-77
Pennell, C A; Mercolino, T J; Grdina, T A et al. (1989) Biased immunoglobulin variable region gene expression by Ly-1 B cells due to clonal selection. Eur J Immunol 19:1289-95
Arnold, L W; Grdina, T A; Whitmore, A C et al. (1988) Ig isotype switching in B lymphocytes. Isolation and characterization of clonal variants of the murine Ly-1+ B cell lymphoma, CH12, expressing isotypes other than IgM. J Immunol 140:4355-63

Showing the most recent 10 out of 22 publications