Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA024144-09S1
Application #
3166336
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1978-08-01
Project End
1988-08-31
Budget Start
1987-09-01
Budget End
1988-08-31
Support Year
9
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Coleman, W B; Grisham, J W; Smith, G J (1994) Morphologic transformation of the C3H 10T1/2 cell line is accompanied by altered expression of the p53 tumor suppressor gene. Carcinogenesis 15:145-52
Coleman, W B; Throneburg, D B; Grisham, J W et al. (1994) Overexpression of c-K-ras, c-N-ras and transforming growth factor beta co-segregate with tumorigenicity in morphologically transformed C3H 10T1/2 cell lines. Carcinogenesis 15:1005-12
Smith, G J; Bell, W N; Grisham, J W (1993) Clonal analysis of the expression of multiple transformation phenotypes and tumorigenicity by morphologically transformed 10T1/2 cells. Cancer Res 53:500-8
Bakewell, W E; Smith, G J; Miller, B E et al. (1993) Confocal laser scanning immunofluorescence microscopy of the pulmonary surfactant system. Association of surfactant protein A with the nucleus of the alveolar type II cell. Lab Invest 68:566-76
Smith, G J; Bagnell, C R; Bakewell, W E et al. (1991) Application of confocal scanning laser microscopy in experimental pathology. J Electron Microsc Tech 18:38-49
Bakewell, W E; Viviano, C J; Dixon, D et al. (1991) Confocal laser scanning immunofluorescence microscopy of lamellar bodies and pulmonary surfactant protein A in isolated alveolar type II cells. Lab Invest 65:87-95
Dent, G A; Ayscue, L H; High, K A et al. (1989) Flow cytometric correlation of the c-myc oncoprotein and cell cycle kinetics of HL60 leukaemia during induced maturation with cytosine arabinoside and dimethylsulphoxide. Cell Tissue Kinet 22:1-11
Black, K A; McFarland, R D; Grisham, J W et al. (1989) S-phase block and cell death in human lymphoblasts exposed to benzo[a]pyrene diol epoxide or N-acetoxy-2-acetylaminofluorene. Toxicol Appl Pharmacol 97:463-72
Dent, G A; Leglise, M C; Pryzwansky, K B et al. (1989) Simultaneous paired analysis by flow cytometry of surface markers, cytoplasmic antigens, or oncogene expression with DNA content. Cytometry 10:192-8
Black, K A; McFarland, R D; Grisham, J W et al. (1989) Cell cycle perturbation and cell death after exposure of a human lymphoblastoid cell strain to N-methyl-N'-nitro-N-nitrosoguanidine. Am J Pathol 134:53-61

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