Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA025820-06
Application #
3167030
Study Section
Biophysics and Biophysical Chemistry A Study Section (BBCA)
Project Start
1979-08-01
Project End
1985-08-31
Budget Start
1984-12-01
Budget End
1985-08-31
Support Year
6
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Weizmann Institute of Science
Department
Type
DUNS #
City
Rehovot
State
Country
Israel
Zip Code
76100
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Cochet, C; Kashles, O; Chambaz, E M et al. (1988) Demonstration of epidermal growth factor-induced receptor dimerization in living cells using a chemical covalent cross-linking agent. J Biol Chem 263:3290-5
Tal, M; Wetzler, M; Josefberg, Z et al. (1988) Sporadic amplification of the HER2/neu protooncogene in adenocarcinomas of various tissues. Cancer Res 48:1517-20
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Livneh, E; Dull, T J; Berent, E et al. (1988) Release of a phorbol ester-induced mitogenic block by mutation at Thr-654 of the epidermal growth factor receptor. Mol Cell Biol 8:2302-8
Seger, R; Yarden, Y; Kashles, O et al. (1988) The epidermal growth factor receptor as a substrate for a kinase-splitting membranal proteinase. J Biol Chem 263:3496-500
Yarden, Y; Schlessinger, J (1987) Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation. Biochemistry 26:1434-42
Yarden, Y; Schlessinger, J (1987) Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor. Biochemistry 26:1443-51
Popliker, M; Shatz, A; Avivi, A et al. (1987) Onset of endogenous synthesis of epidermal growth factor in neonatal mice. Dev Biol 119:38-44
Livneh, E; Reiss, N; Berent, E et al. (1987) An insertional mutant of epidermal growth factor receptor allows dissection of diverse receptor functions. EMBO J 6:2669-76

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