Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA025907-14
Application #
2087422
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1979-07-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1997-11-30
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Crowe, D L; Milo, G E; Shuler, C F (1999) Keratin 19 downregulation by oral squamous cell carcinoma lines increases invasive potential. J Dent Res 78:1256-63
Sun, X L; Li, D; Fang, J et al. (1999) Metastatic conversion of chemically transformed human cells. Gene Expr 8:327-39
Lee, H; Li, D; Prior, T et al. (1997) Ineffectiveness of the presence of H-ras/p53 combination of mutations in squamous cell carcinoma cells to induce a conversion of a nontumorigenic to a tumorigenic phenotype. Cell Biol Toxicol 13:419-34
Wani, G; Noyes, I; Milo, G E et al. (1997) Expression of molecular biomarkers in primary breast tumors implanted into a surrogate host: increased levels of cyclins correlate with tumor progression. Mol Med 3:273-83
Li, D; Yan, H; Chen, J et al. (1996) Malignant conversion of human cells by antisense cDNA to a putative tumor suppressor gene. Carcinogenesis 17:1751-5
Milo, G E; Li, D; Casto, B C et al. (1996) Malignant conversion of chemically transformed normal human cells. Proc Natl Acad Sci U S A 93:5229-34
Chen, J; Milo, G E; Shuler, C F et al. (1996) Xenograft growth and histodifferentiation of squamous cell carcinomas of the pharynx and larynx. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81:197-202
Li, D; Noyes, I; Shuler, C et al. (1995) Cloning and sequencing of CATR1.3, a human gene associated with tumorigenic conversion. Proc Natl Acad Sci U S A 92:6409-13
Milo, G E; Shuler, C F; Lee, H et al. (1995) A conundrum in molecular toxicology: molecular and biological changes during neoplastic transformation of human cells. Cell Biol Toxicol 11:329-45
Milo, G E; Shuler, C F; Stoner, G et al. (1992) Conversion of premalignant human cells to tumorigenic cells by methylmethane sulfonate and methylnitronitrosoguanidine. Cell Biol Toxicol 8:193-205

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