Evaluation of New Chromophore Modified Actinomycin D

Sengupta, Sisir K.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 3R01CA026281-04A2S1
• Application #: 3167225
• Study Section: Experimental Therapeutics Subcommittee 2 (ET)
• Project Start: 1978-12-01
• Project End: 1988-05-31
• Budget Start: 1985-06-01
• Budget End: 1986-05-31
• Support Year: 4
• Fiscal Year: 1986

Institution

• Name: Boston University
• Type: Schools of Medicine
• DUNS #: 604483045
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02118

Publications

Sengupta, S K; Rosenbaum, D P; Sehgal, R K et al. (1988) Enantiomers of 7-(2,3-epoxypropoxy)actinomycin D as dual-action DNA-acting antitumor agents. J Med Chem 31:1540-7

Sehgal, R K; Almassian, B; Rosenbaum, D P et al. (1988) Synthesis and biological properties of actinomycin D chromophoric analogues substituted at carbon 7 with aziridine and cyclopropyl functions. J Med Chem 31:790-3

Sehgal, R K; Almassian, B; Rosenbaum, D P et al. (1987) Synthesis and biological properties of actinomycin D chromophoric analogues substituted at the 7-carbon with aziridine and aminopropoxy functions. J Med Chem 30:1626-31