An Autocrine Basis of Epithelial Growth and Neoplasia

Rheinwald, James

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 7R01CA026656-16
• Application #: 2087517
• Study Section: Pathology B Study Section (PTHB)
• Project Start: 1979-03-01
• Project End: 1995-08-31
• Budget Start: 1994-06-01
• Budget End: 1995-08-31
• Support Year: 16
• Fiscal Year: 1992

Institution

• Name: Brigham and Women's Hospital
• DUNS #: 071723621
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02115

Publications

Schon, M; Rheinwald, J G (1996) A limited role for retinoic acid and retinoic acid receptors RAR alpha and RAR beta in regulating keratin 19 expression and keratinization in oral and epidermal keratinocytes. J Invest Dermatol 107:428-38

Crowe, D L; Hu, L; Gudas, L J et al. (1991) Variable expression of retinoic acid receptor (RAR beta) mRNA in human oral and epidermal keratinocytes;relation to keratin 19 expression and keratinization potential. Differentiation 48:199-208

Hu, L; Crowe, D L; Rheinwald, J G et al. (1991) Abnormal expression of retinoic acid receptors and keratin 19 by human oral and epidermal squamous cell carcinoma cell lines. Cancer Res 51:3972-81

Demetri, G D; Zenzie, B W; Rheinwald, J G et al. (1989) Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro. Blood 74:940-6

Tubo, R A; Rheinwald, J G (1987) Normal human mesothelial cells and fibroblasts transfected with the EJras oncogene become EGF-independent, but are not malignantly transformed. Oncogene Res 1:407-21

La Rocca, P J; Rheinwald, J G (1985) Anchorage-independent growth of normal human mesothelial cells: a sensitive bioassay for EGF which discloses the absence of this factor in fetal calf serum. In Vitro Cell Dev Biol 21:67-72