Chest radiography is the most important diagnostic examination for the detection of asymptomatic lung disorders including cancer and plays a central role in the monitoring of other major cardiopulmonary diseases such as heart disease and pneumonia. Conventional chest radiography is technically difficult due to the large variations in tissue thickness between the lung zones (15 cm) and the mediastinal, diaphragmatic and cardiac portions (30 cm) which can result in 50 fold variations in film exposure. Considering the approximately 10 fold useful exposure range of radiographic film. This condition results in chest radiographs where soft tissue contrast over the thicker body parts is compromised when the lung zones are rendered with maximum film contrast. We have developed an automatic technique of maintaining uniform film contrast over all parts of a chest radiograph by Scanning Equalization Radiography (SER) that regionally tailors the incident patient exposure so the large excursion in film density are eliminated. The technique uses conventional radiographic film and completes an image forming scan in 4.7 seconds. We have demonstrated the technical feasibility of this technique and a clinical study has shown that the exposure consistency characteristic of this technique results improved visualization of normal anatomy and greater diagnostic efficacy. We propose further development of this technique focusing on reducing our current scan time to minimize motion unsharpness, exploring the use of simultaneous energy and intensity equalization to enhance lung tissue subject contrast and testing the feasibility of more efficient methods of SER using multiple scanning beams.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA027823-06
Application #
3167860
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1980-04-01
Project End
1988-03-31
Budget Start
1985-04-01
Budget End
1986-03-31
Support Year
6
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Rochester
Department
Type
Schools of Medicine
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Wandtke, J C; Plewes, D B (1991) Improved imaging of bone with scan equalization radiography. AJR Am J Roentgenol 157:359-64
Wandtke, J C; Plewes, D B (1989) Comparison of scanning equalization and conventional chest radiography. Radiology 172:641-5
Wandtke, J C; Plewes, D B; McFaul, J A (1988) Improved pulmonary nodule detection with scanning equalization radiography. Radiology 169:23-7
Wandtke, J C; Plewes, D B (1985) Improved chest disease detection with scanning equalization radiography. AJR Am J Roentgenol 145:979-83
Wandtke, J C; Plewes, D B (1985) Exposure equalization radiography of the chest: clinical comparison of slit and raster scanning techniques. AJR Am J Roentgenol 144:1171-81
Plewes, D B; Vogelstein, E E (1985) An x-ray collimator design for raster scanning geometries. Phys Med Biol 30:713-21
Wandtke, J C; Plewes, D P; Vogelstein, E (1985) Scanning equalization radiography of the chest: assessment of image quality. AJR Am J Roentgenol 145:973-8