Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA027931-14
Application #
2087662
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1980-05-01
Project End
1996-11-30
Budget Start
1994-12-01
Budget End
1996-11-30
Support Year
14
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Internal Medicine/Medicine
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Milas, L; Fujii, T; Hunter, N et al. (1999) Enhancement of tumor radioresponse in vivo by gemcitabine. Cancer Res 59:107-14
Gregoire, V; Hunter, N R; Brock, W A et al. (1996) Improvement in the therapeutic ratio of radiotherapy for a murine sarcoma by indomethacin plus fludarabine. Radiat Res 146:548-53
Vyas, R C; Frankel, S R; Agbor, P et al. (1996) Probing the pathobiology of response to all-trans retinoic acid in acute promyelocytic leukemia: premature chromosome condensation/fluorescence in situ hybridization analysis. Blood 87:218-26
Pandita, T K; DeRubeis, D (1995) Spontaneous amplification of interstitial telomeric bands in Chinese hamster ovary cells. Cytogenet Cell Genet 68:95-101
Pandita, T K; Hittelman, W N (1995) Evidence of a chromatin basis for increased mutagen sensitivity associated with multiple primary malignancies of the head and neck. Int J Cancer 61:738-43
Gregoire, V; Ruifrok, A C; Price, R E et al. (1995) Effect of intra-peritoneal fludarabine on rat spinal cord tolerance to fractionated irradiation. Radiother Oncol 36:50-5
Pandita, T K; Hittelman, W N (1994) Increased initial levels of chromosome damage and heterogeneous chromosome repair in ataxia telangiectasia heterozygote cells. Mutat Res 310:1-13
Gregoire, V; Hunter, N; Brock, W A et al. (1994) Fludarabine improves the therapeutic ratio of radiotherapy in mouse tumors after single-dose irradiation. Int J Radiat Oncol Biol Phys 30:363-71
Gregoire, V; Hunter, N; Milas, L et al. (1994) Potentiation of radiation-induced regrowth delay in murine tumors by fludarabine. Cancer Res 54:468-74
Gregoire, V; Van, N T; Stephens, L C et al. (1994) The role of fludarabine-induced apoptosis and cell cycle synchronization in enhanced murine tumor radiation response in vivo. Cancer Res 54:6201-9

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