Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA028427-12
Application #
2087731
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1980-07-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
009214214
City
La Jolla
State
CA
Country
United States
Zip Code
92037
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Huang, R P; Fan, Y; deBelle, I et al. (1998) Egr-1 inhibits apoptosis during the UV response: correlation of cell survival with Egr-1 phosphorylation. Cell Death Differ 5:96-106
Xu, W; Baribault, H; Adamson, E D (1998) Vinculin knockout results in heart and brain defects during embryonic development. Development 125:327-37
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Xu, W; Coll, J L; Adamson, E D (1998) Rescue of the mutant phenotype by reexpression of full-length vinculin in null F9 cells;effects on cell locomotion by domain deleted vinculin. J Cell Sci 111 ( Pt 11):1535-44
Adamson, E D; Wiley, L M (1997) The EGFR gene family in embryonic cell activities. Curr Top Dev Biol 35:71-120
Huang, R P; Fan, Y; de Belle, I et al. (1997) Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation. Int J Cancer 72:102-9
Tsark, E C; Adamson, E D; Withers 3rd, G E et al. (1997) Expression and function of amphiregulin during murine preimplantation development. Mol Reprod Dev 47:271-83
Wu, J X; Adamson, E D (1996) Kinase-negative mutant epidermal growth factor receptor (EGFR) expression during embryonal stem cell differentiation favours EGFR-independent lineages. Development 122:3331-42
Huang, R P; Wu, J X; Fan, Y et al. (1996) UV activates growth factor receptors via reactive oxygen intermediates. J Cell Biol 133:211-20

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