Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA031641-11
Application #
2088173
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1982-01-01
Project End
1997-12-31
Budget Start
1995-01-01
Budget End
1997-12-31
Support Year
11
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Temple University
Department
Miscellaneous
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122

  Publications

Kimura, Masatomo; Lehmann, Kiyoko; Gopalan-Kriczky, Prathima et al. (2004) Effect of diet on aflatoxin B1-DNA binding and aflatoxin B1-induced glutathione S-transferase placental form positive hepatic foci in the rat. Exp Mol Med 36:351-7
Hiruma, S; Gopalan-Kriczky, P; Qin, G et al. (2001) Differential effects of acetaminophen pretreatment on hepatic aflatoxin B(1)-DNA binding, cellular proliferation, and aflatoxin B1-induced hepatic foci in rats and hamsters. Cancer Lett 170:117-24
Qin, G; Ning, Y; Su, J et al. (1998) Enhancement of aflatoxin B1-induced enzyme altered hepatic foci in rats by treatment with carbon tetrachloride. Exp Mol Med 30:186-91
Hiruma, S; Kimura, M; Lehmann, K et al. (1997) Potentiation of aflatoxin B1-induced hepatocarcinogenesis in the rat by pretreatment with buthionine sulfoximine. Cancer Lett 113:103-9
Hiruma, S; Qin, G Z; Gopalan-Kriczky, P et al. (1996) Effect of cell proliferation on initiation of aflatoxin B1-induced enzyme altered hepatic foci in rats and hamsters. Carcinogenesis 17:2495-9
Gopalan-Kriczky, P; Hiruma, S; Lotlikar, P D (1994) Effect of glutathione levels on aflatoxin B1-DNA binding in livers and kidneys of male rats and hamsters pretreated with buthionine sulfoximine and dimethylmaleate. Cancer Lett 76:25-30
Gopalan-Kriczky, P; Jensen, D E; Lotlikar, D (1994) Conjugation of microsome generated and synthetic aflatoxin B1-8,9 epoxide and styrene oxide to glutathione by purified glutathione S-transferases from hamster and mouse livers. Cancer Lett 86:83-90
Gopalan, P; Tsuji, K; Lehmann, K et al. (1993) Modulation of aflatoxin B1-induced glutathione S-transferase placental form positive hepatic foci by pretreatment of rats with phenobarbital and buthionine sulfoximine. Carcinogenesis 14:1469-70
Tsuji, K; Gopalan, P; Lehmann, K et al. (1992) Species and sex differences of aflatoxin B1-induced glutathione S-transferase placental form in single hepatocytes. Cancer Lett 66:249-54
Gopalan, P; Jensen, D E; Lotlikar, P D (1992) Glutathione conjugation of microsome-mediated and synthetic aflatoxin B1-8,9-oxide by purified glutathione S-transferases from rats. Cancer Lett 64:225-33

Showing the most recent 10 out of 19 publications