Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA031770-14
Application #
2088205
Study Section
Neurology A Study Section (NEUA)
Project Start
1988-02-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Neurology
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Muldoon, Leslie L; Neuwelt, Edward A (2003) BR96-DOX immunoconjugate targeting of chemotherapy in brain tumor models. J Neurooncol 65:49-62
Varallyay, Peter; Nesbit, Gary; Muldoon, Leslie L et al. (2002) Comparison of two superparamagnetic viral-sized iron oxide particles ferumoxides and ferumoxtran-10 with a gadolinium chelate in imaging intracranial tumors. AJNR Am J Neuroradiol 23:510-9
Kraemer, Dale F; Fortin, David; Neuwelt, Edward A (2002) Chemotherapeutic dose intensification for treatment of malignant brain tumors: recent developments and future directions. Curr Neurol Neurosci Rep 2:216-24
Blakley, Brian W; Cohen, James I; Doolittle, Nancy D et al. (2002) Strategies for prevention of toxicity caused by platinum-based chemotherapy: review and summary of the annual meeting of the Blood-Brain Barrier Disruption Program, Gleneden Beach, Oregon, March 10, 2001. Laryngoscope 112:1997-2001
Smith, Justine R; Rosenbaum, James T; Wilson, David J et al. (2002) Role of intravitreal methotrexate in the management of primary central nervous system lymphoma with ocular involvement. Ophthalmology 109:1709-16
Muldoon, L L; Walker-Rosenfeld, S L; Hale, C et al. (2001) Rescue from enhanced alkylator-induced cell death with low molecular weight sulfur-containing chemoprotectants. J Pharmacol Exp Ther 296:797-805
Remsen, L G; Marquez, C; Garcia, R et al. (2001) Efficacy after sequencing of brain radiotherapy and enhanced antibody targeted chemotherapy delivery in a rodent human lung cancer brain xenograft model. Int J Radiat Oncol Biol Phys 51:1045-9
Doolittle, N D; Muldoon, L L; Brummett, R E et al. (2001) Delayed sodium thiosulfate as an otoprotectant against carboplatin-induced hearing loss in patients with malignant brain tumors. Clin Cancer Res 7:493-500
Osztie, E; Varallyay, P; Doolittle, N D et al. (2001) Combined intraarterial carboplatin, intraarterial etoposide phosphate, and IV Cytoxan chemotherapy for progressive optic-hypothalamic gliomas in young children. AJNR Am J Neuroradiol 22:818-23
Neuwelt, E A; Pagel, M A; Hasler, B P et al. (2001) Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model. Cancer Res 61:7868-74

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