Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA036233-04S1
Application #
3173742
Study Section
Experimental Immunology Study Section (EI)
Project Start
1984-01-01
Project End
1988-02-29
Budget Start
1988-01-01
Budget End
1988-02-29
Support Year
4
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
Schools of Medicine
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90033
Mitchell, M S; Jakowatz, J; Harel, W et al. (1994) Increased effectiveness of interferon alfa-2b following active specific immunotherapy for melanoma. J Clin Oncol 12:402-11
Mitchell, M S; Liggett, P E; Green, R L et al. (1994) Sustained regression of a primary choroidal melanoma under the influence of a therapeutic melanoma vaccine. J Clin Oncol 12:396-401
Quan Jr, W D; Mitchell, M S (1993) Immunology and immunotherapy of melanoma. Cancer Treat Res 65:257-77
Kan-Mitchell, J; Huang, X Q; Steinman, L et al. (1993) Clonal analysis of in vivo activated CD8+ cytotoxic T lymphocytes from a melanoma patient responsive to active specific immunotherapy. Cancer Immunol Immunother 37:15-25
Mitchell, M S; Harel, W; Kan-Mitchell, J et al. (1993) Active specific immunotherapy of melanoma with allogeneic cell lysates. Rationale, results, and possible mechanisms of action. Ann N Y Acad Sci 690:153-66
LeMay, L G; Kan-Mitchell, J; Goedegebuure, P et al. (1993) Detection of melanoma-reactive CD4+ HLA-class I-restricted cytotoxic T cell clones with long-term assay and pretreatment of targets with interferon-gamma. Cancer Immunol Immunother 37:187-94
Mitchell, M S (1992) Chemotherapy in combination with biomodulation: a 5-year experience with cyclophosphamide and interleukin-2. Semin Oncol 19:80-7
Mitchell, M S (1992) Biomodulators in cancer treatment. J Clin Pharmacol 32:2-9
Mitchell, M S (1992) Principles of combining biomodulators with cytotoxic agents in vivo. Semin Oncol 19:51-6
Mitchell, M S; Harel, W; Groshen, S (1992) Association of HLA phenotype with response to active specific immunotherapy of melanoma. J Clin Oncol 10:1158-64

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